Evidence map›Paper›PMID 39565177›Full record

ReviewBlood cancer discovery2025

Venetoclax-Based Combination Regimens in Acute Myeloid Leukemia.

Hannah Goulart, Hagop Kantarjian, Naveen Pemmaraju, Naval Daver, Courtney D DiNardo, Caitlin R Rausch, Farhad Ravandi, Tapan M Kadia

Abstract readReview
In one paragraph

Review in Blood cancer discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Recent advances in CAR T and CAR NK cell therapy for AML.International journal of hematology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hannah GoulartDivision of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-1945-2571
Hagop KantarjianDepartment of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-1908-3307
Naveen PemmarajuDepartment of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-1670-6513
Naval DaverDepartment of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-7103-373X
Courtney D DiNardoDepartment of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-9003-0390
Caitlin R RauschDivision of Pharmacy, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-4166-5717
Farhad RavandiDepartment of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-7621-377X
Tapan M KadiaDepartment of Leukemia, University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-9892-9832

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672University of Texas MD Anderson Cancer Center (MD Anderson) C1100632
6 · The paper itself

Abstract

significanceIn recent years, there has been tremendous interest surrounding the integration of venetoclax into both non-intensive and intensive chemotherapy regimens for AML. However, with this increasing utilization of venetoclax, considerable questions surrounding key issues such as dosing strategies and the practicality of venetoclax administration have arisen. This review highlights the evolution of venetoclax-based regimens in AML and provides a commentary on notable practical considerations when utilizing this agent.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBridged Bicyclo Compounds, HeterocyclicLeukemia, Myeloid, AcuteSulfonamidesAntineoplastic AgentsHumansAntineoplastic AgentsBridged Bicyclo Compounds, HeterocyclicSulfonamidesvenetoclax

Identifiers

PMID39565177
PMCPMC11707511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.