Depression, sleep and pain affect instrumental activities of daily living through cognitive functioning in adults with sickle cell disease: A report from the Sickle Cell Disease Implementation Consortium.
Jennifer N Longoria, Kristen E Howell, Jerlym S Porter, Marsha Treadwell, Allison A King, Victor Gordeuk, Nirmish Shah, Christina M Abrams, Sarah McCuskee, Siera Gollan and 3 more
Article in British journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors.
Jennifer N LongoriaDepartment of Psychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID https://orcid.org/0000-0003-0621-6438
Kristen E HowellEpidemiology and Biostatistics, Texas A&M University, College Station, Texas, USA.
Jerlym S PorterDepartment of Psychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Marsha TreadwellDepartment of Pediatrics, Division of Hematology, University of California San Francisco, Oakland, California, USA.
Allison A KingDepartment of Pediatrics and Medicine, Washington University, St. Louis, Missouri, USA.
Andrew M HeitzerDepartment of Psychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID https://orcid.org/0000-0003-0582-3850
Sickle Cell Disease Implementation Consortium
Funding
Data Coordinating Center for Sickle Cell Disease Implementation Consortium (SCDIC)U24HL133948 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI JACOBS, SARA RUBIN, KRONER, BARBARA L · 2016 to 2021
$7.3M
New York City Sickle Cell Implementation Science ConsortiumU01HL133997 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RICHARDSON, LYNNE D. · 2016 to 2021
$5.4M
The Implementation of Cognitive Screening and Educational Support to Improve Outcomes of Adolescents and Young Adults with Sickle Cell Disease: From Clinic to the Community and BackU01HL133994 · NHLBI · WASHINGTON UNIVERSITY · PI KING, ALLISON A · 2016 to 2021
$5.2M
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)U01HL134042 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GORDEUK, VICTOR R, HIRSCHTICK, JANA · 2016 to 2021
$5.1M
Implementation of Medical Homes for Evidence Based Care of Adolescents and Adults with Sickle Cell DiseaseU01HL134004 · NHLBI · AUGUSTA UNIVERSITY · PI GIBSON, ROBERT WILLIAM, KUTLAR, ABDULLAH · 2016 to 2021
$5.0M
Improving SCD Care using Web-based Guidelines, Nurse Care Managers and Peer Mentors in Primary Care and Emergency Departments in Central North CarolinaU01HL133964 · NHLBI · DUKE UNIVERSITY · PI SHAH, NIRMISH R, TANABE, PAULA · 2016 to 2021
$4.8M
RE-aiming at Hydroxyurea Adherence for Sickle cell with mHealth (RE-HASH)U01HL133996 · NHLBI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HANKINS, JANE SILVA, KLESGES, LISA M · 2016 to 2021
$4.6M
SC-Links - Linking the Sickle Cell Community, Providers and Systems to Improve Sickle Cell Disease CareU01HL134007 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TREADWELL, MARSHA J, VICHINSKY, ELLIOTT P · 2016 to 2021
$4.1M
Implementation of a Sickle Cell Enhanced Novel Care Network in South Carolina (iSCENSC)U01HL133990 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FLOREZ, HERMES JOSE · 2016 to 2021
$4.1M
School Readiness Intervention for Preschool Children with Sickle Cell DiseaseK23HL166697 · NHLBI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Andrew M Heitzer · 2023 to 2026
Depression, disrupted sleep and pain are common comorbidities in sickle cell disease. We tested (1) if these comorbidities are associated with attention/executive functioning, processing speed and instrumental activities of daily living (IADLs), which describe complex skills that support independence, and (2) if cognitive symptoms mediate the relationship between comorbidities and IADLs. Participants (n = 2417) completed patient-reported outcome measures through the Sickle Cell Disease Implementation Consortium. Mean age of participants was 28 years and HbSS/Sβ
Indexed as
Activities of Daily LivingAnemia, Sickle CellCognitionDepressionPainSleep Wake DisordersAdolescentAdultComorbidityExecutive FunctionFemaleHumansMaleMiddle AgedSleepYoung Adultcognitivedepressioninstrumental activities of daily livingpainsickle cell diseasesleep
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Depression, sleep and pain affect instrumental activities of daily living through cognitive functioning in adults with sickle cell disease: A report from the Sickle Cell Disease Implementation Consortium. · full record | OpenQuestion