Evidence map›Paper›PMID 39564525›Full record

ArticleFrontiers in neuroscience2024

Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study.

Bhaswati Roy, Mariana Thedim, Chiewlin Liew, Rajesh Kumar, Susana Vacas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bhaswati RoyDepartment of Anesthesiology and Perioperative Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Mariana ThedimDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Chiewlin LiewDepartment of Anesthesiology and Perioperative Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Rajesh KumarDepartment of Anesthesiology and Perioperative Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Susana VacasDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

Funding

Mechanisms Mediating Postoperative Neurocognitive DisordersK23GM132795 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VACAS, SUSANA · 2019 to 2023
$1.0M
Blood Brain Barrier Dysfunction and Perioperative Neurocognitive Disorders in older adultsR21AG070269 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KUMAR, RAJESH, VACAS, SUSANA · 2020 to 2020
$429k
NIA NIH HHS R21 AG070269NIGMS NIH HHS K23 GM132795
6 · The paper itself

Abstract

Background: Obese patients have worse outcomes after surgery and are at increased risk for perioperative neurocognitive disorders (PND). Our aim was to detail the cognitive trajectories of patients undergoing bariatric surgery (BS) and map distinct structural brain changes using magnetic resonance imaging (MRI) to better understand the association between the vulnerable brain, surgery, and the arc of PND. Methods: Prospective pilot study with longitudinal comprehensive cognitive assessments and MRI were performed on obese patients scheduled for BS. We analyzed baseline cognitive function and high-resolution T1-/T2-weighted brain images on 19 obese patients [age, 54 (9) years, BMI, 40 (36, 42) kg m Results: At baseline, obese patients had significant brain tissue changes seen in MRI and decreased cognitive scores compared to controls (MoCA 26 vs 28, Conclusions: Bariatric surgery resulted in worsening of preexisting brain structural integrity and lower cognitive function for obese patients compared to baseline. These distinct brain lesions are consistent with specific domains of cognition. Most of these changes reverted to patient's baseline condition within six months after surgery.

Indexed as

bariatric surgerycognitive dysfunctionmagnetic resonance imagingneuropsychological testsobesityperioperative neurocognitive disorderspostoperative deliriumsurgery

Identifiers

PMID39564525
PMCPMC11573770

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.