Evidence map›Paper›PMID 39564442›Full record

ArticleTurkish journal of emergency medicine

Unexpected consequences: A case of ketamine-induced seizure in procedural sedation.

Adem Az, Yunus Doğan

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Turkish journal of emergency medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06741930 (Potential Pro-Convulsive Properties of Ketamine and Its Effects on EEG During Procedural Sedation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06741930 phase4completednot on this map

Potential Pro-Convulsive Properties of Ketamine and Its Effects on EEG During Procedural Sedation: A Comparative Evaluation With Midazolam and Propofol

TypeinterventionalSponsorHaseki Training and Research HospitalRan2024 to 2025Enrolled300ConditionsEpilepsy, SeizureArmsKetamine, Midazolam, Propofol
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adem AzDepartment of Emergency Medicine, Haseki Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.ORCID https://orcid.org/0000-0002-7204-6185
Yunus DoğanDepartment of Emergency Medicine, Mus State Hospital, Mus, Türkiye.ORCID https://orcid.org/0000-0002-9456-8777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a 32-year-old male who underwent ketamine procedural sedation and experienced a generalized tonic-clonic seizure. Despite its rapid onset and favorable tolerance profile, this case emphasizes the potential convulsive side effects of ketamine, which is commonly used for procedural sedation. While ketamine has shown promise in treating acute pain, refractory status epilepticus, and treatment-resistant depression and schizophrenia, it is associated with side effects such as hallucinations, visual disturbances, dizziness, nausea, and vomiting. The patient in this case received a carefully titrated dose of 40 mg of ketamine intravenously and underwent successful shoulder reduction while under sedation. However, within 60 s of receiving the ketamine, the patient experienced a 60-s seizure that was stopped with the administration of 5 mg of diazepam intravenously. The patient was hospitalized for further evaluation, including an electroencephalography (EEG) that showed no abnormalities. This case highlights the need for health-care professionals to be aware of the potential convulsive side effects of ketamine and to carefully monitor patients who receive ketamine sedation.

Indexed as

Adverse effectketamineprocedural sedationseizure

Identifiers

PMID39564442
PMCPMC11573176

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.