Evidence map›Paper›PMID 39564037›Full record

ArticleCureus2024

Frequency Distributions of Alleles and Genotypes and Lung Cancer Risk of Polymorphisms DCK, SLC29A1, and SLC29A3 in South Indian Healthy Population.

Devika T, Ganesapandian Mahalakshmi, K Mythili, Katiboina Srinivasa Rao, Srinivasamurthy Suresh Kumar, Biswajit Dubashi, Deepak G Shewade

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Devika TDepartment of Pharamcology, Guntur Medical College, Guntur, IND.
Ganesapandian MahalakshmiDepartment of Pharmacology, Nandha Medical College and Hospital, Erode, IND.
K MythiliDepartment of Physiology, Government Siddhartha Medical College, Vijayawada, IND.
Katiboina Srinivasa RaoDepartment of Pharmacology, All India Institute of Medical Sciences, Mangalagiri, IND.
Srinivasamurthy Suresh KumarDepartment of Pharmacology, Ras Al Khaimah College of Medical Sciences, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, ARE.
Biswajit DubashiDepartment of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.
Deepak G ShewadeDepartment of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Gemcitabine, a cytotoxic drug, is used to treat a variety of solid tumors, such as pancreatic, lung, and breast malignancies. The efficiency rates for gemcitabine have decreased due to an increase in genetic instability. The association between gene polymorphisms and the efficacy of gemcitabine therapy may be better known by understanding the intricacies of genetics that target a few or more genes in drug-targeting metabolic pathways. Moreover, several studies have documented differences in the therapeutic response among various ethnicities to gemcitabine chemotherapy. Therefore, the purpose of this study was to determine the normative frequencies of gene polymorphisms linked to the metabolic pathway of gemcitabine (

Indexed as

dckgemcitabinepolymorphismsslc29a1slc29a3snps

Identifiers

PMID39564037
PMCPMC11576072

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.