Evidence map›Paper›PMID 39564010›Full record

ReviewCureus2024

C-reactive Protein (CRP) in Patients With Myocarditis: A Systematic Review and Meta-Analysis.

Bushra Ghulam, Zahira Bashir, Amber Khurshid Akram, Qudsia Umaira Khan, Mamoon Qadir, Shokat Hussain, Amna Akbar, Sarosh Khan Jadoon

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bushra GhulamBiochemistry, Islamic International Medical College, Islamabad, PAK.
Zahira BashirBiochemistry, Mohi-ud-Din Islamic Medical College, Mirpur, PAK.
Amber Khurshid AkramBiochemistry, Mohi-ud-din Islamic Medical College, Mirpur, PAK.
Qudsia Umaira KhanPhysiology, Combined Military Hospital Medical College and Institute of Dentistry, Lahore, PAK.
Mamoon QadirInterventional Cardiology, Kulsum International Hospital, Islamabad, PAK.
Shokat HussainMedicine, Combined Military Hospital, Muzaffarabad, PAK.
Amna AkbarEmergency and Accident, District Headquarter Hospital, Muzaffarabad, PAK.
Sarosh Khan JadoonGeneral Surgery, Sheikh Khalifa Bin Zayed (SKBZ) Combined Military Hospital, Muzaffarabad, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocarditis is a type of cardiovascular disease related to inflammation of cardiac muscle which can be even fatal to some extent. Early and simple diagnosis is crucial for this complication; however, complex or machine-based methods, such as histological tests, x-rays, electrocardiograms, etc., are usually used for its detection. C-reactive protein (CRP) is a biomarker that naturally elevates during inflammation. Therefore, we tried to understand the correlation between CRP and myocarditis. We primarily identified 451 studies from PubMed, Google Scholar, and ScienceDirect and ultimately selected four studies as eligible. We identified the mean difference (MD) in CRP levels between the myocarditis patients and healthy controls. The study quality, outliers, sensitivity, significance, and heterogeneity were also checked. The MD (6.03 (95%CI: 2.41-9.64), p<0.00001) corresponds to a higher and significant CRP level in myocarditis as compared to the control group. The study quality was found to be high with no bias or outliers and the heterogeneity was also determined to be high (I

Indexed as

acute myocarditiscardiovasculardiagnosisinflammationprognosis

Identifiers

PMID39564010
PMCPMC11573699

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.