Evidence map›Paper›PMID 39563991›Full record

ReviewThe Journal of innovations in cardiac rhythm management2024

The Role of Cardiac Magnetic Resonance to Predict Response to Cardiac Resynchronization Therapy: A Systematic Review and Meta-analysis.

Nazima Khatun, Alejandro Sanchez-Nadales, Jonathan Francois, Mohammed Hussein, Muhammed Atere, Yasser Rodriguez, Jose Baez-Escudero, Adam Budzikowski

Abstract readReview
In one paragraph

Review in The Journal of innovations in cardiac rhythm management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Tissue characterization using cardiac magnetic resonance imaging and response to cardiac resynchronization therapy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nazima KhatunDepartment of Internal Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Alejandro Sanchez-NadalesRobert and Suzanne Tomsich Department of Cardiology, Department of Cardiovascular Disease, Cleveland Clinic Florida, Weston Campus, FL, USA.
Jonathan FrancoisDivision of Cardiovascular Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Mohammed HusseinRobert and Suzanne Tomsich Department of Cardiology, Department of Cardiovascular Disease, Cleveland Clinic Florida, Weston Campus, FL, USA.
Muhammed AtereDivision of Cardiovascular Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Yasser RodriguezRobert and Suzanne Tomsich Department of Cardiac Pacing and Electrophysiology, Department of Cardiovascular Disease, Cleveland Clinic Florida, Weston Campus, FL, USA.
Jose Baez-EscuderoRobert and Suzanne Tomsich Department of Cardiac Pacing and Electrophysiology, Department of Cardiovascular Disease, Cleveland Clinic Florida, Weston Campus, FL, USA.
Adam BudzikowskiDivision of Cardiovascular Medicine, Electrophysiology Section, SUNY Downstate Medical Center, Brooklyn, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac resynchronization therapy (CRT) has revolutionized heart failure (HF) management, offering benefits in morbidity, mortality, and symptom alleviation. However, optimal response rates are not universally achieved, necessitating enhanced patient-selection strategies. Myocardial scar patterns, quantified by delayed-enhancement cardiac magnetic resonance (DE-CMR), have been implicated in CRT outcomes. We conducted a meta-analysis of observational studies assessing CRT responses by performing a systematic literature search using PubMed, Embase, Ovid MEDLINE, Scopus, the Cochrane Library, ScienceDirect, and the Web of Science. Scar burden, left ventricular ejection fraction (LVEF), left ventricular end-systolic volume (LVESV), and left ventricular end-diastolic volume (LVEDV) were evaluated. CRT response rates among ischemic and non-ischemic cardiomyopathy patients were also explored. This meta-analysis incorporated eight studies meeting the eligibility criteria. CRT responders exhibited a significantly lower scar burden (-11.7%; 95% confidence interval, 6.6%-16.8%) compared to non-responders, supporting the predictive value of scar quantification (

Indexed as

Cardiac magnetic resonancecardiac resynchronization therapyheart failuremeta-analysisscar burden

Identifiers

PMID39563991
PMCPMC11573304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.