Evidence map›Paper›PMID 39563796›Full record

ArticleACS medicinal chemistry letters2024

Semisynthetic Tetramate-Containing Fungal Metabolites with Activity against

Thilini Peramuna, Gwendolyn E Wood, Ziwei Hu, Karen L Wendt, Laarni Kendra T Aguila, Caroline M Kim, Adam S Duerfeldt, Robert H Cichewicz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Anti-Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thilini PeramunaNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.
Gwendolyn E WoodDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington 98104, United States.
Ziwei HuDepartment of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Stephenson Life Sciences Research Center, Norman, Oklahoma 73019, United States.
Karen L WendtNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.
Laarni Kendra T AguilaDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington 98104, United States.
Caroline M KimDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington 98104, United States.
Adam S DuerfeldtDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55414, United States.ORCID https://orcid.org/0000-0002-3130-9890
Robert H CichewiczNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.ORCID https://orcid.org/0000-0003-0744-4117

Funding

Early Stage Discovery of Natural Products Targeting Anaerobic Protozoal PathogenR33AI119713 · NIAID · UNIVERSITY OF OKLAHOMA · PI CICHEWICZ, ROBERT HENRY · 2017 to 2019
$1.4M
Fungal natural products targeting antimicrobial resistant Mycoplasma genitaliumR21AI153863 · NIAID · UNIVERSITY OF OKLAHOMA · PI CICHEWICZ, ROBERT HENRY, WOOD, GWENDOLYN · 2021 to 2022
$441k
NIAID NIH HHS R21 AI153863NIAID NIH HHS R33 AI119713
6 · The paper itself

Abstract

Tetramic acid-containing natural products are well known for their promising biological activity against various diseases. In our previous study, we reported fungal-derived tetramic acid-containing natural products with activity against

Identifiers

PMID39563796
PMCPMC11571018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.