Evidence map›Paper›PMID 39563721›Full record

ArticleTobacco induced diseases2024

Association of the use of e-cigarettes, combustible cigarettes or dual use with hypertension and mortality in hypertensive individuals: Insights from NHANES 2015-2018.

Yi Lu, Hao Jiang, Yin Ren, Meixiang Wang, Aili Yuan, Jing Wu, Zhongbao Ruan, Xiangwei Ding

Abstract read
In one paragraph

Article in Tobacco induced diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. [Effects of particulate matter pollution on human skin].Dermatologie (Heidelberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi Lu *Department of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Hao Jiang *Department of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Yin RenDepartment of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Meixiang WangDepartment of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Aili YuanDepartment of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Jing WuDepartment of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Zhongbao RuanDepartment of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Xiangwei DingDepartment of Cardiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCombustible cigarettes have been shown to increase hypertension risk. Nevertheless, data on the association between electronic cigarettes (e-cigarettes), as well as dual use of e-cigarettes and combustible cigarettes, and hypertension, are limited.

methodsThis study aims to examine the association of the use of e-cigarettes, combustible cigarettes or dual use with hypertension. Data from the 2015-2018 National Health and Nutrition Examination Survey were used. Weighted logistic regression models were employed to determine the relationship between cigarette use and hypertension. Weighted Cox proportional hazard regression models were developed to evaluate the association between electronic/combustible cigarettes or dual use and mortality in hypertensive individuals.

resultsA total of 7696 participants (median age 47 years; 51.76% females) were included. In the adjusted model, the groups of e-cigarette use, combustible cigarette use, and dual use were found to be significantly associated with the risk of hypertension with AOR and 95% CI of 1.56 (1.01-2.42), 1.29 (1.01-1.64) and 1.83 (1.03-3.27) respectively. Significant trends of the relationship between cigarette use and hypertension were observed. The median follow-up for mortality was 38 months. Current e-cigarette use showed a positive correlation with all-cause death and cardiovascular death compared to never e-cigarette use with HR and 95% CI of 1.30 (1.01-1.66) and 1.30 (1.01-1.67), respectively. The trend of association of e-cigarette use with mortality was significant.

conclusionsThis study shows that electronic/combustible cigarette use or dual use increased risk of hypertension. E-cigarettes were associated with a higher risk of all-cause mortality and cardiovascular mortality. Notably, the increased risk of mortality among e-cigarette users may be due to underlying, pre-existing comorbidities related to prior combustible cigarette use. Findings from the study provide evidence of the benefits of e-cigarette use control, especially among individuals with hypertension.

Indexed as

combustible cigarettedual usee-cigarettehypertensionNHANES

Identifiers

PMID39563721
PMCPMC11574958

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.