Evidence map›Paper›PMID 39563463›Full record

ArticleJournal of the American Geriatrics Society2025

Social determinants of health and mild cognitive impairment in a diverse community sample.

Mary Ganguli, Erin Jacobsen, Ruopu Song, Isabella Wood, Ellen J Kinnee, Tiffany F Hughes, Beth E Snitz, Chung-Chou H Chang

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mary GanguliDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2762-7105
Erin JacobsenDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ruopu SongDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Isabella WoodDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ellen J KinneeUniversity Center for Social and Urban Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Tiffany F HughesPublic Health Program, College of Graduate Studies, Midwestern University, Glendale, Arizona, USA.
Beth E SnitzDepartment of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Chung-Chou H ChangDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Funding

Mild Cognitive Impairment: A Prospective Community StudyR37AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Carmen Andreescu, MARY GANGULI · 2021 to 2026
$18.2M
Risk factors for MCI and Dementia in a Diverse Senior CohortR01AG058549 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GANGULI, MARY · 2018 to 2022
$3.7M
NIA NIH HHS R01 AG058549NIA NIH HHS R01AG05854901NIA NIH HHS R37 AG023651NIA NIH HHS R37AG023651
6 · The paper itself

Abstract

backgroundThe associations between community-wide social determinants of health and mild cognitive impairment (MCI) among individuals warrant investigation.

methodsAmong 2830 dementia-free individuals aged 65+ years in a community-based US study, we examined cross-sectional associations of MCI (Clinical Dementia Rating = 0.5) with the following potential social determinants of health: at the census tract or block group level obtained from public sources: neighborhood disadvantage (Area Deprivation Index, ADI), air pollution with fine particulate matter (PM

resultsUnadjusted logistic regression models found higher odds ratios (OR, 95% CI) for MCI with higher ADI (1.01, 1.003-1.02), higher PM

conclusionsIn this cohort, several community-wide social/environmental factors were associated with MCI. While clinicians should continue to encourage older adults to modify their individual risk factors, policy changes are needed to mitigate social determinants of health in the community.

Indexed as

Cognitive DysfunctionNeighborhood CharacteristicsSocial Determinants of HealthAgedAged, 80 and overAir PollutionCross-Sectional StudiesFemaleHumansMaleResidence CharacteristicsRisk FactorsUnited Statesagingcognitionepidemiologyrisk factors

Identifiers

PMID39563463
PMCPMC11826000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.