Evidence map›Paper›PMID 39563413›Full record

ArticleMolecular horticulture2024

Horizontal transfer of plasmid-like extrachromosomal circular DNAs across graft junctions in Solanaceae.

Aijun Zhang, Tingjin Wang, Lu Yuan, Yuxin Shen, Ke Liu, Bin Liu, Kexin Xu, Mohamed A Elsadek, Yiting Wang, Liang Wu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular horticulture, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Graft Biology in the CRISPR Era: From Tissue Fusion to Genome Compatibility.Plant-environment interactions (Hoboken, N.J.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Aijun Zhang *Department of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Tingjin Wang *Department of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Lu Yuan *Department of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Yuxin Shen *Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Ke LiuDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Bin LiuDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Kexin XuDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Mohamed A ElsadekDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Yiting WangInstitute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
Liang WuDepartment of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Zhenyu QiDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Jingquan YuDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Mingfang ZhangDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China. mfzhang@zju.edu.cn.
Liping ChenDepartment of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China. chenliping@zju.edu.cn.ORCID http://orcid.org/0000-0002-3102-0640

Funding

Science and Technology Program of Zhejiang Province 2022SNJF027
6 · The paper itself

Abstract

The transfer of genetic material between stocks and scions of grafted plants has been extensively studied; however, the nature and frequency of the transferred material remain elusive. Here, we report a grafting system involving woody goji as the stock and herbaceous tomato as the scion, which was developed using in vitro and in vivo approaches; the results confirmed horizontal transfer of multiple nuclear DNA fragments from donor goji cells to recipient tomato cells. Tomato tissues containing goji donor DNA fragments at or near the grafting junctions had a perennial-biased anatomical structure, from which roots or shoots were regenerated. Most of the fragments were plasmid-like extrachromosomal circular DNAs (eccDNAs) present in the regenerants derived from the cells and in their asexual offspring. Plants with transferred eccDNAs in regenerated roots or shoots (designated "Go-tomato") were grown perennially and showed excellent agronomic performance. The present study provides new insights into the replication, expression, and potential function of eccDNAs in the pleiotropic traits of Go-tomato. Mobile eccDNAs offer evidence of stock-to-scion horizontal DNA transfer beyond chromosomes and organelles, thereby contributing to the molecular understanding of graft-induced genetic variation, evolution, and breeding.

Indexed as

Asexual offspring inheritabilityDistant graftingEccDNA transferGojiPleiotropic traitsTomato

Identifiers

PMID39563413
PMCPMC11577957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.