Evidence map›Paper›PMID 39563322›Full record

ArticleBMC public health2024

Iron deficiency anemia and its association with cognitive function among adolescents in the Ashanti Region - Ghana.

Francis Agyemang Yeboah, Joyce Bioh, Benjamin Amoani, Alfred Effah, Ebenezer Senu, Oscar Simon Olympio Mensah, Alex Agyei, Samuel Kwarteng, Samuel Kwame Sopuruchi Agomuo, Stephen Opoku and 3 more

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Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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10citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Francis Agyemang YeboahDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Joyce BiohDepartment of Chemical Pathology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Benjamin AmoaniDepartment of Biomedical Science, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Alfred EffahDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. alfredeffah97@gmail.com.
Ebenezer SenuDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Oscar Simon Olympio MensahDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Alex AgyeiDepartment of Chemical Pathology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Samuel KwartengDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Samuel Kwame Sopuruchi AgomuoDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Stephen OpokuDivision of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, USA.
Samuel Kekeli AgordzoDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Ebenezer Krampah AidooDepartment of Medical Laboratory Technology, Accra Technical University, Accra, Ghana.
Samuel Asamoah SakyiDepartment of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIron deficiency anemia (IDA) remains a global health concern, and has been associated with cognitive decline. However, very few studies have explored the association between IDA and cognitive function among Ghanaians. We assessed the association between IDA and cognitive function among adolescents in the Ashanti region, Ghana.

methodsThis cross-sectional study involved 250 adolescents from Kumasi, Ghana. Sociodemographic and dietary data were obtained using a well-structured questionnaire. Blood samples were drawn for estimation of ferritin and complete blood count. The Test of Non-verbal Intelligence (TONI-4) was used to assess cognitive function. Binary logistic regression was used to determine the predictors of cognitive function.

resultsThe prevalence of IDA was 30.4%, which was higher among adolescents with poor cognitive performance test scores (CPTS) (71%). Being female [aOR = 0.32, 95% CI (0.10-0.99), p = 0.0480)], father having junior high education [aOR = 0.08, 95% CI (0.02-0.45), p = 0.0040)], being in a category B school [aOR = 0.26, 95% CI (0.09-0.81), p = 0.0200)] and C [aOR = 0.08, 95% CI (0.02-0.40), p = 0.0020)] and non-fruit consumption [aOR = 0.18, 95% CI (0.06-0.52), p = 0.0010)], were significantly associated with lower likelihood of having very good cognitive function. Moreover, ferritin (r = 0.451, p < 0.001) and hemoglobin (r = 0.402, p < 0.001) demonstrated a moderate positive correlation with CPTS.

conclusionThe prevalence of IDA is high in our study population and was linked with poor cognitive function. Adolescents with IDA had low cognitive performance test scores. High levels of hemoglobin and ferritin showed a moderate correlation with higher cognitive performance. These findings suggest that adolescents' cognitive function may be moderately influenced by IDA, highlighting the potential impact of iron status on cognitive outcomes.

Indexed as

Anemia, Iron-DeficiencyAdolescentCognitionCognitive DysfunctionCross-Sectional StudiesFemaleGhanaHumansMalePrevalenceAdolescentsanemiaCognitive functionIron deficiency

Identifiers

PMID39563322
PMCPMC11575446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.