Evidence map›Paper›PMID 39563311›Full record

Observational studyBMC musculoskeletal disorders2024

Hip strengthening exercise dosage is not associated with clinical improvements after total hip arthroplasty - a prospective cohort study (the PHETHAS-1 study).

Merete Nørgaard Madsen, Lone Ramer Mikkelsen, Michael Skovdal Rathleff, Kristian Thorborg, Thomas Kallemose, Thomas Bandholm

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03109821 (Home-based Rehabilitation Following a Total Hip Replacement - do Patients Follow the Exercise Prescription and How Does it Relate to Postoperative Recovery? The Pragmatic Home-Based Exercise After Total Hip Arthroplasty Silkeborg 1), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03109821 completednot on this map

Home-based Rehabilitation Following a Total Hip Replacement - do Patients Follow the Exercise Prescription and How Does it Relate to Postoperative Recovery? The Pragmatic Home-Based Exercise After Total Hip Arthroplasty Silkeborg 1 (PHETHAS-1) Trial

TypeobservationalSponsorCentral Jutland Regional HospitalRan2017 to 2020Enrolled94ConditionsArthroplasty, Replacement, HipArmsHome-based exercise
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Merete Nørgaard MadsenElective Surgery Centre, Silkeborg Regional Hospital, Silkeborg, Denmark. merete.madsen@clin.au.dk.
Lone Ramer MikkelsenElective Surgery Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.
Michael Skovdal RathleffCenter for General Practice, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Kristian ThorborgSports Orthopedic Research Center-Copenhagen, Department of Orthopaedic Surgery, Copenhagen University Hospital, Amager and Hvidovre, Hvidovre, Denmark.
Thomas KallemoseDepartment of Clinical Research, Copenhagen University Hospital, Amager and Hvidovre, Hvidovre, Denmark.
Thomas BandholmPhysical Medicine and Rehabilitation Research - Copenhagen (PMR-C), Department of Occupational and Physical Therapy, Copenhagen University Hospital, Amager and Hvidovre, Hvidovre, Denmark.

Funding

The Aase and Ejnar Danielsen Foundation 10-002170The Danish Rheumatism Association R139-A3844The Danish Rheumatism Association R167-5669
6 · The paper itself

Abstract

backgroundPostoperative rehabilitation exercise is commonly prescribed after total hip arthroplasty (THA), but its efficacy compared to no or minimal rehabilitation exercise has been questioned. Preliminary efficacy would be indicated if a dose-response relationship exists between performed exercise dose and degree of postoperative recovery. The objective was to evaluate the preliminary efficacy of home-based rehabilitation using elastic band exercise on performance-based function after THA, based on the association between performed exercise dose and change in performance-based function (gait speed) from 3 (start of intervention) to 10 weeks (end of intervention) after surgery.

methodsA prospective cohort study was conducted. Following primary THA, patients were prescribed home-based rehabilitation exercise using elastic bands. Performed exercise dose (repetitions/week) was objectively measured using attached sensor technology. Primary outcome was change in gait speed (40 m fast-paced walk test). Secondary outcomes included patient-reported hip disability. In the primary analysis, a linear regression model was used.

resultsNinety-four patients (39 women) with a median age of 66.5 years performed a median of 339 exercise repetitions/week (1st-3rd quartile: 209-549). Across outcomes, participants significantly improved from 3 to 10-week follow-up. The association between performed exercise dose and change in mean gait speed was 0.01 m/s [95% CI: -0.01; 0.02] per 100 repetitions.

conclusionsWe found no indication of preliminary efficacy of home-based rehabilitation exercise using elastic bands, as no significant and clinically relevant associations between performed exercise dose and changes in outcomes were present. Trials comparing postoperative rehabilitation exercise with no exercise early after THA are warranted.

trial registrationPre-registered: ClinicalTrials.gov (Identifier: NCT03109821, 12/04/2017).

Indexed as

Arthroplasty, Replacement, HipExercise TherapyAgedFemaleHip JointHumansMaleMiddle AgedMuscle StrengthProspective StudiesRecovery of FunctionTreatment OutcomeWalking SpeedComplianceDose-responseExercise therapyHip arthroplastyRehabilitation

Identifiers

PMID39563311
PMCPMC11577667

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.