Evidence map›Paper›PMID 39562835›Full record

ArticleScientific reports2024

Multimodal assessment of brain stiffness variation in healthy subjects using magnetic resonance elastography and ultrasound time-harmonic elastography.

Stefan Klemmer Chandía, Jakob Schattenfroh, Spencer T Brinker, Heiko Tzschätzsch, Ingolf Sack, Tom Meyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stefan Klemmer ChandíaDepartment of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Jakob SchattenfrohDepartment of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Spencer T BrinkerDepartment of Neurology, Yale School of Medicine, 333 Cedar St, New Haven, CT, 06510, USA.
Heiko TzschätzschDepartment of Medical Informatics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Invalidenstraße 90, 10115, Berlin, Germany.
Ingolf SackDepartment of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Tom MeyerDepartment of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany. tom.meyer@charite.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance elastography (MRE) is a noninvasive brain stiffness mapping method. Ultrasound-based transtemporal time-harmonic elastography (THE) is emerging as a cost-effective, fast alternative that has potential applications for bedside monitoring of intracranial pressure. We aim to investigate the accuracy of THE in comparison to MRE performed in the brain. Ten healthy volunteers (25-40 years old) underwent multifrequency MRE (20-35 Hz) and THE (27-56 Hz). Fiducial-marker-based optical tracking of the ultrasound field of view was used to align THE to 3D MRE. THE- and MRE-derived shear wave speed (SWS) was determined as a measure of brain stiffness and averaged within regions of various depths for cross-modality correlation analysis. MRE-measured SWS ranged from 1.0 to 1.3 m/s and was negatively correlated with age (R

Indexed as

BrainElasticity Imaging TechniquesHealthy VolunteersAdultFemaleHumansMagnetic Resonance ImagingMaleUltrasonographyFiducial markersHuman brainMagnetic resonance elastographyOptical trackingTranstemporal ultrasound time-harmonic elastography

Identifiers

PMID39562835
PMCPMC11576992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.