Evidence map›Paper›PMID 39562793›Full record

ReviewMicrosystems & nanoengineering2024

Sound innovations for biofabrication and tissue engineering.

Mengxi Wu, Zhiteng Ma, Zhenhua Tian, Joseph T Rich, Xin He, Jianping Xia, Ye He, Kaichun Yang, Shujie Yang, Kam W Leong and 2 more

Abstract readReview
In one paragraph

Review in Microsystems & nanoengineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  10. SonoPIN enables precise, noninvasive, and efficient intracellular delivery of PROTACs.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  11. Article
  12. Review
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  18. Enhancing cancer therapyLab on a chip · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mengxi Wu *School of Mechanical Engineering, Dalian University of Technology, Dalian, 116086, Liaoning, China.ORCID http://orcid.org/0000-0003-0086-5349
Zhiteng Ma *Thomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Zhenhua TianDepartment of Mechanical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24060, USA.
Joseph T RichDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.ORCID http://orcid.org/0000-0002-6249-2093
Xin HeSchool of Mechanical Engineering, Dalian University of Technology, Dalian, 116086, Liaoning, China.
Jianping XiaThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.ORCID http://orcid.org/0000-0001-9902-0228
Ye HeThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.ORCID http://orcid.org/0000-0001-7363-1063
Kaichun YangThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Shujie YangThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Kam W LeongDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA. kam.leong@columbia.edu.ORCID http://orcid.org/0000-0002-8133-4955
Luke P LeeRenal Division and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. lplee@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-1436-4054
Tony Jun HuangThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA. tony.huang@duke.edu.

Funding

Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) R01GM132603Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) UG3TR002978Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) UH3TR002142National Science Foundation (NSF) ECCS-1807601
6 · The paper itself

Abstract

Advanced biofabrication techniques can create tissue-like constructs that can be applied for reconstructive surgery or as in vitro three-dimensional (3D) models for disease modeling and drug screening. While various biofabrication techniques have recently been widely reviewed in the literature, acoustics-based technologies still need to be explored. The rapidly increasing number of publications in the past two decades exploring the application of acoustic technologies highlights the tremendous potential of these technologies. In this review, we contend that acoustics-based methods can address many limitations inherent in other biofabrication techniques due to their unique advantages: noncontact manipulation, biocompatibility, deep tissue penetrability, versatility, precision in-scaffold control, high-throughput capabilities, and the ability to assemble multilayered structures. We discuss the mechanisms by which acoustics directly dictate cell assembly across various biostructures and examine how the advent of novel acoustic technologies, along with their integration with traditional methods, offers innovative solutions for enhancing the functionality of organoids. Acoustic technologies are poised to address fundamental challenges in biofabrication and tissue engineering and show promise for advancing the field in the coming years.

Identifiers

PMID39562793
PMCPMC11577104

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.