Evidence map›Paper›PMID 39562781›Full record

ArticlePsycho-oncology2024

Social Support and Treatment Delays in Breast Cancer Patients Within an Integrated Health Care System.

Candyce H Kroenke, Marilyn L Kwan, Scarlett L Gomez, Veronica Shim, Isaac J Ergas, Janise Roh, Lawrence H Kushi

Abstract read
In one paragraph

Article in Psycho-oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Lorlatinib and neurocognitive adverse events: characterization, risk factors, and the potentially mitigative role of social support.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Candyce H KroenkeDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID 0000-0002-6128-3118
Marilyn L KwanDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Scarlett L GomezDepartment of Epidemiology and Biostatistics, University of California, Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
Veronica ShimDepartment of Surgery, Kaiser Permanente Northern California, Oakland, California, USA.
Isaac J ErgasDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Janise RohDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Lawrence H KushiDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.

Funding

Prospective Study of Breast Cancer SurvivorshipR01CA105274 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2004 to 2014
$19.9M
Infrastructure for Pathways, a Prospective Study of Breast Cancer SurvivorshipU01CA195565 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI AMBROSONE, CHRISTINE B., KUSHI, LAWRENCE H · 2016 to 2025
$18.8M
Social networks and disparities in health behaviors and breast cancer outcomes in immigrant womenR01CA230440 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KROENKE, CANDYCE H · 2019 to 2024
$3.2M
An Electronic Health Record-Based Tool to Identify Newly Diagnosed Breast Cancer Patients at Risk of Low Social SupportR01CA253028 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KROENKE, CANDYCE H · 2020 to 2025
$2.6M
Social networks, breast cancer treatment, and survivalK07CA187403 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KROENKE, CANDYCE H · 2015 to 2019
$914k
American Cancer SocietyNCI NIH HHS K07 CA187403NCI NIH HHS R01 CA105274NCI NIH HHS R01 CA230440NCI NIH HHS R01 CA253028NCI NIH HHS U01 CA195565
6 · The paper itself

Abstract

objectiveWe evaluated associations between social support and delays to surgery and adjuvant chemotherapy in a cohort of women with breast cancer (BC) from a large integrated healthcare system in Northern California.

methodsThis study included 3983 women from the Pathways Study diagnosed from 2005 to 2013 with stages I-IV BC, who had surgery as their first line of treatment and who responded to the Medical Outcomes Study Social Support survey ∼2 months following diagnosis. A second set of analyses included those receiving adjuvant chemotherapy (N = 1761). We used log binomial regression to evaluate associations of social support, and types of support, with relative prevalence of delays from diagnosis to definitive surgery > 30 days, delays to chemotherapy from diagnosis > 90 days, and delays to chemotherapy from definitive surgery > 60 days. We further examined analyses stratified by sociodemographic factors and disease severity.

resultsTwenty-one percent had surgery delays and 18.3% had chemotherapy delays from diagnosis (24.7% from surgery). Adjusted for covariates, women in the lowest tertile of social support were more likely to have delays to surgery (prevalence ratio (PR) = 1.27, 95% confidence interval (CI):1.08-1.48, p-continuous = 0.01) and chemotherapy (PR = 1.48, 95% CI: 1.08-2.02, p = 0.05) from diagnosis, due to associations of low tangible and emotional support with delays. We noted no effect modification in these analyses. By contrast, low social support was related to chemotherapy delays from diagnosis in women < 54 (PR = 1.96, 95% CI: 1.33-2.88) but not ≥ 54 (PR = 1.09, 95% CI: 0.79-1.49) years of age, p-interaction = 0.05. Other tests of effect modification were nonsignificant.

conclusionsLow social support was associated with delays to BC surgery and chemotherapy.

Indexed as

Breast NeoplasmsDelivery of Health Care, IntegratedSocial SupportTime-to-TreatmentAdultAgedCaliforniaChemotherapy, AdjuvantFemaleHumansMastectomyMiddle AgedNeoplasm StagingTreatment Delaybreast cancercancerchemotherapydelaysoncologysocial networkssocial supportsurgerywomen

Identifiers

PMID39562781
PMCPMC11817851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.