Evidence map›Paper›PMID 39562694›Full record

Observational studyScientific reports2024

Red blood cell distribution width to albumin ratio as a predictor of mortality in ICU patients with community acquired bacteremia.

Xiaoxi Shan, Jing Jiang, Wei Li, Lixia Dong

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Predictive value of platelet count-related ratios for severity in biliary Escherichia coli and Klebsiella pneumonia bloodstream infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoxi Shan *Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, 300041, Tianjin, China.
Jing Jiang *Department of Respiratory and Critical Care Medicine, Yantai Yuhuangding Hospital, 20 Yuhuangding East Road, 264200, Yantai, Shandong, China.
Wei Li *Department of Respiratory and Critical Care Medicine, Yantai Yuhuangding Hospital, 20 Yuhuangding East Road, 264200, Yantai, Shandong, China. 50719618@qq.com.
Lixia Dong *Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, 300041, Tianjin, China. luckydonglixia@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bloodstream infections are globally occurring life-threatening diseases that impose significant societal and economic burdens. This study explored the red cell distribution width (RDW) to albumin ratio (RAR), a novel index derived from RDW, to investigate its relationship with prognosis of bacteremia using propensity score matching (PSM). This retrospective observational cohort study included patients with bacteremia admitted to Yantai Yuhuangding Hospital's intensive care units from June 2019 to December 2022. PSM was performed to adjust for confounding factors. The relationship between RAR and mortality was assessed using receiver operating characteristic curves, multivariate, and Kaplan-Meier analyses. A total of 411 patients were included. The RAR threshold of 5.824% /g/dL was determined by maximizing the Youden index; the study population was divided into two groups based on this cutoff value. After PSM, 125 pairs of score-matched patients were generated. Using logistic regression analysis, patients with RAR ≥ 5.824% /g/dL exhibited significantly higher mortality than did those with RAR < 5.824% /g/dL in the entire cohort (OR = 3.926, 95% confidence interval (CI): 2.408-6.400, p < 0.001) and the PSM subset (OR = 2.460, 95% CI: 1.411-4.289, p = 0.040). RAR results were consistent when treated as continuous or four-categorical variables (based on quartiles). Similar outcomes were found for 28- and 90-day mortality and septic shock. The areas under the curves of RAR were 0.735, significantly higher than those of albumin or RAR alone. RAR emerges as an independent risk factor for mortality and septic shock in critically ill patients with community-acquired bacteremia, whether considered a continuous or categorized variable, irrespective of PSM adjustment.

Indexed as

BacteremiaErythrocyte IndicesIntensive Care UnitsAgedCommunity-Acquired InfectionsFemaleHumansMaleMiddle AgedPrognosisPropensity ScoreRetrospective StudiesROC CurveSerum AlbuminSerum AlbuminBacteremiaBloodstream infectionCritically illRed blood cell distribution

Identifiers

PMID39562694
PMCPMC11576904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.