Evidence map›Paper›PMID 39562632›Full record

ArticleScientific reports2024

Metabolic flexibility to lipid during exercise is not associated with metabolic health outcomes in individuals without obesity.

Rodrigo Fernández-Verdejo, Juan Gutiérrez-Pino, Thomas Hayes-Ortiz, Hermann Zbinden-Foncea, Claudio Cabello-Verrugio, Mayalen Valero-Breton, Mauro Tuñón-Suárez, Ronald Vargas-Foitzick, Jose E Galgani

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rodrigo Fernández-VerdejoPennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA, USA. rodrigo.fernandez@pbrc.edu.
Juan Gutiérrez-PinoCentro de Fisiología del Ejercicio y Metabolismo, Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Thomas Hayes-OrtizCentro de Fisiología del Ejercicio y Metabolismo, Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Hermann Zbinden-FonceaCentro de Fisiología del Ejercicio y Metabolismo, Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Claudio Cabello-VerrugioLaboratory of Muscle Pathology, Fragility and Aging, Department of Biological Sciences, Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
Mayalen Valero-BretonFacultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Madrid, España.
Mauro Tuñón-SuárezCentro de Fisiología del Ejercicio y Metabolismo, Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Ronald Vargas-FoitzickCentro de Fisiología del Ejercicio y Metabolismo, Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Jose E GalganiPennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA, USA. jgalgani@uc.cl.

Funding

The Louisiana Center for Advancing Uplifting Scientists Careers in Health, Nutrition, Obesity, and Diabetes Research (LAUNCHED)U24DK132740 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk, Robert Lee Newton · 2022 to 2026
$3.4M
Agencia Nacional de Investigación y Desarrollo (ANID) - Millennium Science Initiative Program ICN09_016 / ICN 2021_045ANID/CONICYT FONDECYT Iniciación 11180361ANID/CONICYT FONDECYT Regular 1220551Fondo Nacional de Desarrollo Científico y Tecnológico 1241947NIDDK NIH HHS U24 DK132740Proyecto Núcleo UNAB DI-03-23/NUC
6 · The paper itself

Abstract

A low metabolic flexibility to lipid (MetF-lip) in skeletal muscle may promote ectopic lipid accumulation, thus inducing metabolic disturbances. We aimed to determine the association between MetF-lip in skeletal muscle and metabolic health outcomes in individuals without obesity. We also explored the association between MetF-lip and the inflammatory signaling pathway in skeletal muscle. This was a cross-sectional study in 17 individuals aged (median [IQR]) 55.4 [48.6, 58.5] years, with a BMI of 24.4 [22.6, 26.0] kg/m

Indexed as

ExerciseLipid MetabolismMuscle, SkeletalObesityCross-Sectional StudiesFemaleHumansMaleMetabolic SyndromeMiddle AgedBody compositionCardiorespiratory FitnessInsulin resistanceMitogen-activated protein kinases

Identifiers

PMID39562632
PMCPMC11576753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.