Evidence map›Paper›PMID 39562626›Full record

ArticleScientific reports2024

Evaluation of plasma activated liquids for the elimination of mixed species biofilms within endoscopic working channels.

Naomi Northage, Vasyl Shvalya, Martina Modic, Thorsten Juergens, Sascha Eschborn, Malcolm J Horsburgh, James L Walsh

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Bacterial bioluminescence for the real time andAntimicrobial agents and chemotherapy · 2026
    Article
  2. Review
  3. Article
  4. [Advances in Novel Disinfection Technologies for Biofilm-Associated Nosocomial Infections].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naomi NorthageCentre for Plasma Microbiology, Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, L69 3GJ, UK.
Vasyl ShvalyaLaboratory for Gaseous Electronics, Jožef Stefan Institute, Ljubljana, 1000, Slovenia.
Martina ModicLaboratory for Gaseous Electronics, Jožef Stefan Institute, Ljubljana, 1000, Slovenia.
Thorsten JuergensR&D Endoscopy Reprocessing Systems, Olympus Surgical Technologies Europe, Olympus Winter & Ibe GmbH, Kuehnstraße 61, 22045, Hamburg, Germany.
Sascha EschbornR&D Endoscopy Reprocessing Systems, Olympus Surgical Technologies Europe, Olympus Winter & Ibe GmbH, Kuehnstraße 61, 22045, Hamburg, Germany.
Malcolm J HorsburghInfection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L69 7BE, UK.
James L WalshLaboratory for Gaseous Electronics, Jožef Stefan Institute, Ljubljana, 1000, Slovenia. james.l.walsh@york.ac.uk.

Funding

Engineering and Physical Sciences Research Council EP/N021347Javna Agencija za Raziskovalno Dejavnost RS J2-4451
6 · The paper itself

Abstract

The use of reusable flexible endoscopes has increased dramatically over the past decade, however despite improvements in endoscope reprocessing, the continued emergence of endoscopy-associated outbreaks as a result of multi-drug resistant bacteria has highlighted the need for a new approach to disinfection. Here, the use of plasma activated liquids (PALs) for the elimination of mixed species biofilm contamination within the working channels of endoscopes was evaluated. Cold atmospheric pressure plasma was used to chemically activate water and a commercially available pH buffered peracetic acid to create PALs. Polytetrafluoroethylene endoscope surrogate test pieces were contaminated with clinically relevant mixed species biofilms. The efficacy of PALs for the decontamination of narrow lumens was compared against the commercial disinfectant. Plasma activation was found to increase the antibiofilm capabilities of pH buffered peracetic acid by introducing reactive chemical species into the solution. Disinfection of endoscopic test pieces with plasma activated disinfectant (PAD) resulted in a 7.30 log

Indexed as

BiofilmsDisinfectantsDisinfectionEndoscopesPlasma GasesEquipment ContaminationHumansPeracetic AcidDisinfectantsPeracetic AcidPlasma GasesCold atmospheric plasmaEndoscope reprocessingFlexible endoscopesHigh level disinfection.Plasma activated liquidsReactive oxygen and nitrogen species

Identifiers

PMID39562626
PMCPMC11576748

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.