Evidence map›Paper›PMID 39561574›Full record

ArticleInternational journal of surgery case reports2024

Nanocarbon localization and 68Ga-DOTA-NOC scan in the diagnosis and management of neuroendocrine tumors (NETs): A case report.

Ke Wang, Chengshuai Si, Peng Shao, Yuepeng Cao, Jin Zhang, Liu Yang

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ke WangDepartment of Colorectal Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing 210009, China.
Chengshuai SiDepartment of Colorectal Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing 210009, China. Electronic address: scalpel_wielder@njmu.edu.cn.
Peng ShaoDepartment of Colorectal Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing 210009, China.
Yuepeng CaoDepartment of Colorectal Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing 210009, China. Electronic address: mf1535001@smail.nju.edu.cn.
Jin ZhangDepartment of Invasive Technology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing 210009, China. Electronic address: wangnannan@stu.njmu.edu.cn.
Liu YangDepartment of Colorectal Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing 210009, China. Electronic address: yangliu@njmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionReports of rectal neuroendocrine tumor (R-NET) are relatively rare. There is a lack of experience in how to accurately locate and resect metastatic lateral lymph nodes. CASE PRESENTATION: We present a challenging case. The patient was diagnosed with rectal neuroendocrine tumor. After endoscopic submucosal dissection (ESD), this patient came to hospital for reexamination. The imaging results indicated the presence of left lateral lymph node metastasis, so total mesorectal excision (TME) plus lateral lymph node dissection(LLND) was performed. One year later, PET-CT was reexamined again, using a contrast agent targeted at somatostatin receptor. The result showed residual metastatic lymph nodes. We used nanocarbon combined with coil to accurately locate the metastatic lymph nodes and finally successfully resected the lymph node. The patient recovered and was discharged 5 days after the operation. DISCUSSION: Surgery is the most effective method for treating rectal neuroendocrine tumors. However, it is still challenging to accurately detect and locate metastatic lymph nodes after surgery. 68Ga-DOTA-NOC is a special contrast agent that targets somatostatin receptors, and somatostatin receptors are highly expressed in NETs. Using it can clearly trace whether the lateral lymph nodes are metastasized. Nanocarbon localization has been used for the localization of various tumors. We combined it with coils and effectively located the metastatic lymph nodes. This localization method has great potential.

conclusionSurgical resection is the most effective way to treat rectal neuroendocrine tumors. Nanocarbon combined with coils can effectively locate metastatic lymph nodes, which is helpful for accurate resection later. And 68Ga-DOTA-NOC can assist in detection of metastatic lymph nodes.

Indexed as

68Ga-DOTA-NOCLymph node dissectionNanocarbon localizationNeuroendocrine neoplasmRectal cancer

Identifiers

PMID39561574
PMCPMC11615929

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