Evidence map›Paper›PMID 39560861›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2025

Trends in syncope testing and admissions in the USA from 2006 through 2019.

Mohammed Ruzieh, Chen Bai, Stephen E Kimmel, Zachary D Goldberger, Osama Dasa, John W Petersen, Madeline Smoot, Emily S Edwards, Sujay R Kamisetty, Mamoun T Mardini

Abstract read
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In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammed RuziehDivision of Cardiovascular Medicine, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, PO BOX 100288, Gainesville, FL, 32610, USA. Moh.ruzieh@gmail.com.ORCID http://orcid.org/0000-0002-7796-8701
Chen BaiDepartment of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Stephen E KimmelDepartment of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, 32610, USA.
Zachary D GoldbergerDivision of Cardiovascular Medicine, Department of Medicine, College of Medicine, University of Wisconsin, Madison, WI, USA.
Osama DasaDivision of Cardiovascular Medicine, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, PO BOX 100288, Gainesville, FL, 32610, USA.
John W PetersenDivision of Cardiovascular Medicine, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, PO BOX 100288, Gainesville, FL, 32610, USA.
Madeline SmootDivision of Cardiovascular Medicine, University of Virginia, Charlottesville, VA, USA.
Emily S EdwardsDepartment of Medicine, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Sujay R KamisettyDepartment of Medicine, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Mamoun T MardiniDepartment of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSyncope is common, with bimodal distribution through life, peaking in adolescence and in the elderly, and overall increases in incidence with age among both men and women. In this context, syncope-related visits to emergency departments (ED), hospitalizations, and testing are a significant healthcare cost burden. Ultimately, understanding the volume of testing types and settings of syncope encounters may aid in more effective healthcare utilization and high value care for this patient population.

methodsData for this study were collected from the Truven Health Analytics MarketScan Database from 2006 to 2019. This database contains both commercially insured patients and those with Medicare coverage. Patients with the diagnosis of syncope were identified using International Classification of Diseases (ICD)-9 and -10 codes. We assessed the incidence of various tests for syncope evaluation and ED disposition for the study period.

resultsThe incidence of syncope among the study cohort rose from nine per 1000 patients to 13 per 1000 patients during the study period. The incidence of testing for syncope among multiple domains (neurologic, cardiac, blood testing) decreased in some categories, but routine testing remained prevalent. Women had a significantly lower incidence of testing in most testing domains. Discharge rate from the ED for patients presenting with syncope remained stable during the study period. However, admission rate to the hospital for those aged > 65 years increased during the study time.

conclusionTesting and admissions for syncope remain prevalent and are drivers of healthcare-associated costs. There is a clear need for further work in developing a focused approach in the evaluation of syncope patients in order to mitigate healthcare costs and improve outcomes.

Indexed as

HospitalizationSyncopeAdolescentAdultAgedAged, 80 and overDatabases, FactualEmergency Service, HospitalFemaleHumansIncidenceMaleMiddle AgedUnited StatesYoung AdultHealthcare costsLow-yield testingSyncope

Identifiers

PMID39560861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.