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ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

A comprehensive review on the green synthesis of silver nanoparticles from marine sources.

Janagandhan Palanisamy, Vinothkumar Suruli Palanichamy, Ganesan Vellaichamy, Parthasarathi Perumal, Jayaraman Vinayagam, Seshan Gunalan, Senthilkumar Gnanavadivel Prabhakaran, Purushoth Prabhu Thiraviam, Fasna Musthafa, Ashok Kumar Balaraman and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Gellan Gum/Alginate Films Containing BiogenicMolecules (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Janagandhan PalanisamyDepartment of Pharmaceutical Chemistry, Pannai College of Pharmacy, Dindigul - 624005, India (Affiliated to The Tamil Nadu Dr. M.G.R. Medical University, Tamil Nadu, Chennai, India.
Vinothkumar Suruli PalanichamyDepartment of Pharmaceutical Chemistry, Pannai College of Pharmacy, Dindigul - 624005, India (Affiliated to The Tamil Nadu Dr. M.G.R. Medical University, Tamil Nadu, Chennai, India.
Ganesan VellaichamyDepartment of Pharmaceutical Chemistry, Pannai College of Pharmacy, Dindigul - 624005, India (Affiliated to The Tamil Nadu Dr. M.G.R. Medical University, Tamil Nadu, Chennai, India.
Parthasarathi PerumalDepartment of Molecular and Cell Biology, Greensmed Labs, Chennai, 600097, Tamil Nadu, India.
Jayaraman VinayagamDepartment of Molecular and Cell Biology, Greensmed Labs, Chennai, 600097, Tamil Nadu, India.
Seshan GunalanDepartment of Molecular and Cell Biology, Greensmed Labs, Chennai, 600097, Tamil Nadu, India.
Senthilkumar Gnanavadivel PrabhakaranDepartment of Pharmaceutical Chemistry, Srinivasan College of Pharmaceutical Sciences, Samayapuram, Trichy, 621 112, India.
Purushoth Prabhu ThiraviamDepartment of Pharmacognosy, C.L. Baid Metha College of Pharmacy, Chennai, 600096, India.
Fasna MusthafaDepartment of Molecular and Cell Biology, Greensmed Labs, Chennai, 600097, Tamil Nadu, India.
Ashok Kumar BalaramanCentre for Research and Innovation, University of Cyberjaya, Persiaran Bestari, Cyber 11, 63000, Cyberjaya, Selangor, Malaysia. drashokbalaraman@gmail.com.
Suresh RathinasamyDepartment of Molecular and Cell Biology, Greensmed Labs, Chennai, 600097, Tamil Nadu, India. greensmedlabs@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary purpose of this review is to explore the green synthesis of silver nanoparticle (AgNP) using natural biomolecules derived from marine sources. This review aims to evaluate the effectiveness of environmentally friendly approaches for synthesizing AgNPs and to examine their potential applications across various fields such as medicine, biotechnology, and environmental remediation. The key research question focuses on understanding how marine biomolecules, including polysaccharides, proteins, enzymes, amino acids, alkaloids, and vitamins, contribute to the formation of AgNPs and how these green-synthesized nanoparticles retain their functional properties. This review systematically examines current literature on the green synthesis of AgNPs, focusing on marine-derived biomolecules such as polysaccharides, proteins, and alkaloids. The methodology includes analyzing green synthesis techniques and comparing them with traditional chemical methods to highlight environmental benefits and overall efficiency. Various marine species, such as seagrass and seaweed, are explored as potent agents in the reduction of silver ions. The findings reveal that green synthesis of AgNPs using marine biomolecules is not only environmentally sustainable but also retains the desirable properties of the nanoparticles, such as antimicrobial, antioxidant, and anticancer activities. Additionally, the green-synthesized AgNPs show significant potential applications in mosquito control, wound healing, and anticancer therapies. Green synthesis of AgNPs using marine sources presents a viable and sustainable alternative to conventional chemical methods, significantly reducing the environmental impact of nanoparticle production while ensuring biocompatibility and functional integrity. This approach holds promise for diverse applications in biomedicine, environmental remediation, and beyond. Further research is recommended to address challenges in scaling up production and commercialization.

Indexed as

Aquatic OrganismsGreen Chemistry TechnologyMetal NanoparticlesSilverAnimalsHumansSilverBiological activitiesGreen synthesisMarine sourceSilver nanoparticleSynthesis method

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.