Evidence map›Paper›PMID 39560384›Full record

ArticlemSphere2024

CRISPR-Cas9-based approaches for genetic analysis and epistatic interaction studies in

Samuel Steiner, Craig R Roy

Abstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Bacterial Puppeteering: How the Stealth BacteriumPathogens (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samuel SteinerDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0009-0007-5073-3340
Craig R RoyDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-4490-440X

Funding

High Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2M
The Role of Coxiella Effector Proteins in Infection and DiseaseR56AI182383 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2024 to 2024
$625k
Defining epistatic interactions among Coxiella burnetii effector proteins using a CRISPRi approachR21AI171333 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2022 to 2023
$461k
NIAID NIH HHS R21 AI171333NIAID NIH HHS R56 AI182383NIH HHS S10 OD030363
6 · The paper itself

Abstract

IMPORTANCE: Understanding the genetic mechanisms that enable

Indexed as

Coxiella burnetiiCRISPR-Cas SystemsEpistasis, GeneticGene EditingAnimalsBacterial ProteinsHumansPhenotypeBacterial Proteinsbase editingCoxiella burnetiiCRISPRCRISPRiintracellular infection

Identifiers

PMID39560384
PMCPMC11656778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.