Evidence map›Paper›PMID 39560378›Full record

ArticleSleep2025

Evaluating the performance of open-source and proprietary processing of actigraphy sleep estimation in children with suspected sleep disorders: a comparison with polysomnography.

Aliye B Cepni, Sarah Burkart, Xuanxuan Zhu, James White, Olivia Finnegan, Srihari Nelakuditi, Michael Beets, David Brown Iii, Russell Pate, Gregory Welk and 7 more

Abstract readComparative Study
In one paragraph

Article in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Aliye B CepniHealth and Human Performance Department, University of Houston, Houston, TX, USA.ORCID 0000-0002-6303-8378
Sarah BurkartDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.ORCID 0000-0002-0840-1680
Xuanxuan ZhuDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.
James WhiteDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.
Olivia FinneganDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.ORCID 0000-0003-0625-1479
Srihari NelakuditiDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.ORCID 0000-0001-5990-394X
Michael BeetsDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.
David Brown IiiDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.
Russell PateDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.
Gregory WelkDepartment of Kinesiology, Iowa State University, Ames, IA, USA.
Massimiliano de ZambottiSRI International, Menlo Park, CA, USA.ORCID 0000-0002-0057-5977
Rahul GhosalDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.
Yuan WangDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.
Bridget ArmstrongDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.ORCID 0000-0002-1909-8170
Elizabeth AdamsDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.ORCID 0000-0002-5602-8470
Vincent van HeesAccelting, Almere, The Netherlands.
R Glenn WeaverDepartment of Exercise Science, University of South Carolina, Columbia, SC, USA.

Funding

Targeting Behavioral Adjustment and Healthy Lifestyle in Preschool-Age Children Using an Integrated Family-Based InterventionP20GM130420 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI GOODRUM, NADA MUSSAD · 2020 to 2024
$11.2M
Biomedical-Behavioral Interface: Prevention and Developmental Sciences TrainingT32GM081740 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PRINZ, RONALD J · 2008 to 2022
$4.5M
Validity and Utility of Consumer-based Wearable Fitness Trackers to Monitor Free-Living Physical Activity Energy Expenditure and Sleep in Children 5-12 Years OldR01DK129215 · NIDDK · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI Robert G Weaver · 2022 to 2026
$3.0M
Behavioral-Biomedical Interface: Translational and Prevention Sciences TrainingT32GM145226 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MICHAEL W BEETS, RONALD J PRINZ · 2023 to 2026
$1.2M
Utility and feasibility of activity type to augment consumer wearable-based physical activity energy expenditure prediction equations using heartrate and movement in childrenF31DK136205 · NIDDK · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI WHITE III, JAMES W. · 2023 to 2024
$83k
Leveraging Embedded Mobile Device Sensors for Detection of Children's Mobile Screen Use: Examining Feasibility and PerformanceF31HD115296 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI Olivia Finnegan · 2025 to 2026
$76k
NICHD NIH HHS F31 HD115296NIDDK NIH HHS F31 DK136205NIDDK NIH HHS R01 DK129215NIDDK NIH HHS R01DK129215NIGMS NIH HHS P20 GM130420NIGMS NIH HHS T32 GM081740NIGMS NIH HHS T32GM081740NIGMS NIH HHS T32 GM145226
6 · The paper itself

Abstract

STUDY

objectivesEvaluate the performance of actigraphy-based open-source and proprietary sleep algorithms compared to polysomnography in children with suspected sleep disorders.

methodsIn a sleep clinic, 110 children (5-12 years, 54% female, 50% black, 82% with sleep disorders) wore wrist-placed ActiGraph GT9X during overnight polysomnography. Actigraphy data were scored as sleep or wake using open-source GGIR and proprietary ActiLife software. Discrepancy and epoch-by-epoch analyses were conducted to assess agreement between algorithms and polysomnography, along with equivalence testing.

resultsThe open-source vanHees2015 algorithm showed good accuracy (79.5% ± 12.0%), sensitivity (81.1% ± 13.5%), and specificity (66.0% ± 23.8%) for sleep detection but was outperformed by the proprietary ActiLife algorithms. The magnitude and trend of bias for total sleep time (TST), sleep efficiency (SE), sleep onset latency, and wake after sleep onset were similar between algorithms. TST and SE were statistically equivalent for the Cole-Kripke (Actilife) and vanHees2015 algorithms compared to the Sadeh (Actilife) algorithm. The Cole-Kripke (ActiLife) demonstrated higher sensitivity (90.5%) to detect sleep but lower specificity (61.2%) than Cole-Kripke (GGIR) (sensitivity: 62.7%, specificity: 79.9%). Sadeh and Cole-Kripke estimated sleep outcomes were not statistically equivalent between implementations in ActiLife and GGIR.

conclusionsThe open-source vanHees2015 algorithm performed well but slightly worse than the proprietary ActiLife algorithms in children. The open-source nature vanHees2015 makes it ideal for clinical pediatric use. Implementation of the Sadeh and Cole-Kripke algorithms in the proprietary ActiLife and open-source GGIR software yield different sleep estimates, so comparisons between studies using these different implementations should be avoided.

Indexed as

ActigraphyPolysomnographySleepSleep Wake DisordersAlgorithmsChildChild, PreschoolFemaleHumansMaleSensitivity and SpecificityactigraphyGGIRpediatricspediatrics—sleep apneascoring

Identifiers

PMID39560378
PMCPMC11985398

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.