Trial reportJournal of the American Medical Informatics Association : JAMIA2025
Efficacy of the mLab App: a randomized clinical trial for increasing HIV testing uptake using mobile technology.
Trial report in Journal of the American Medical Informatics Association : JAMIA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03803683 (mLab App for Improving Uptake of Rapid HIV Self-testing and Linking Youth to Care), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
mLab App for Improving Uptake of Rapid HIV Self-testing and Linking Youth to Care
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluating the effectiveness of digital health interventions for HIV prevention and treatment adherence among transgender populations: a systematic review and meta-analysis.Frontiers in microbiology · 2025Pooled it
- Feasibility and Usability of an mHealth App (mLab+) to Guide Users Through HIV and Syphilis Self-Testing: Pilot Randomized Controlled Trial.JMIR formative research · 2025Trial
- Different Classes of HIV-Preventive Behavioral Intention Among Youths Vulnerable to HIV Acquisition.AIDS and behavior · 2025Trial
- Efficacy of an Interactive Life Simulation Gaming App on Improving HIV Testing Uptake Among Adolescents and Young Adults at Risk for HIV: Results of a Randomized Controlled Trial.JMIR serious games · 2026Article
- Inclusion of underserved young people in digital public health interventions for mental health, sexual health and substance use: A systematic review and intervention component analysis.Internet interventions · 2026Review
- Psychometric evaluation of the Spanish-language version of the health information technology usability evaluation scale (Health-ITUES).International journal of medical informatics · 2026Article
- Detailed HIV Self-Testing Patterns Derived from Paradata in the mLab App Clinical Trial.AIDS and behavior · 2026Article
- Exploring digital health user engagement: General app usage patterns from a clinical trial with the mLab App.PLOS digital health · 2026Article
- A multi-site laboratory evaluation of the MEDSCAN application for automated POC-CCA interpretation.Frontiers in parasitology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveTo determine the efficacy of the mLab App, a mobile-delivered HIV prevention intervention to increase HIV self-testing in MSM and TGW. MATERIALS AND
methodsThis was a randomized (2:2:1) clinical trial of the efficacy the mLab App as compared to standard of care vs mailed home HIV test arm among 525 MSM and TGW aged 18-29 years to increase HIV testing.
resultsThe mLab App arm participants demonstrated an increase from 35.1% reporting HIV testing in the prior 6 months compared to 88.5% at 6 months. In contrast, 28.8% of control participants reported an HIV test at baseline, which only increased to 65.1% at 6 months. In a generalized linear mixed model estimating this change and controlling for multiple observations of participants, this equated to control participants reporting a 61.2% smaller increase in HIV testing relative to mLab participants (P = .001) at 6 months. This difference was maintained at 12 months with control participants reporting an 82.6% smaller increase relative to mLab App participants (P < .001) from baseline to 12 months. DISCUSSION AND
conclusionFindings suggest that the mLab App is well-supported, evidence-based, behavioral risk-reduction intervention for increasing HIV testing rates as compared to the standard of care, suggesting that this may be a useful behavioral risk-reduction intervention for increasing HIV testing among young MSM.
trial registrationThis trial was registered with Clinicaltrials.gov NCT03803683.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.