Evidence map›Paper›PMID 39560147›Full record

ArticleAutism : the international journal of research and practice2025

"You should smile more": Population-level sex differences in smiling also exist in autistic people.

Casey J Zampella, Julia Parish-Morris, Jessica Foy, Meredith Cola, Robert T Schultz, John D Herrington

Abstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Casey J ZampellaChildren's Hospital of Philadelphia, USA.ORCID 0000-0002-7973-8520
Julia Parish-MorrisChildren's Hospital of Philadelphia, USA.
Jessica FoyChildren's Hospital of Philadelphia, USA.
Meredith ColaChildren's Hospital of Philadelphia, USA.ORCID 0000-0001-6737-6828
Robert T SchultzChildren's Hospital of Philadelphia, USA.
John D HerringtonChildren's Hospital of Philadelphia, USA.

Funding

Optimized Affective Computing Measures of Social Processes and Negative Valence in Youth PsychopathologyR01MH125958 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI HERRINGTON, JOHN DAVID, STORCH, ERIC A. · 2021 to 2025
$4.5M
Predicting Autism and Social Functioning from Computer Vision Analyses of Motor Synchrony During Dyadic InteractionsR01MH118327 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI SCHULTZ, ROBERT THOMAS · 2019 to 2023
$3.7M
Digitizing Human Vocal Interaction to Understand and Diagnose AutismR01DC018289 · NIDCD · CHILDREN'S HOSP OF PHILADELPHIA · PI PARISH-MORRIS, JULIA · 2020 to 2024
$3.1M
NCATS NIH HHS L30 TR004965NIDCD NIH HHS R01 DC018289NIMH NIH HHS L30 MH127731NIMH NIH HHS R01 MH118327NIMH NIH HHS R01 MH125958
6 · The paper itself

Abstract

Societal expectations for social-emotional behavior differ across sexes; however, diagnostic definitions of autism do not account for this when delineating "typical" versus "atypical." This study examines sex differences in autism in one behavior associated with strong gender biases: smiling. Computer vision was used to quantify smiling in 60 autistic (20 female) and 67 neurotypical (25 female) youth during conversations. Effects of sex and diagnosis were examined on degree of smiling, smile prototypicality, changes in smiling, and impact of smiling on interaction quality. Sex differences in smiling persisted across diagnosis groups: females smiled more than males, and their smiles were more prototypical. Autistic youth smiled less, and less prototypically, than neurotypical youth, with no sex by diagnosis interactions. In autism, the association between smile activity and interaction quality approached statistical significance, seemingly driven by autistic males but not females. Findings are consistent with population trends for females to smile more during social exchanges and "display rules" requiring more positive expressivity from females. Autism has historically been defined based on differences between autistic and neurotypical

Indexed as

Autism Spectrum DisorderAutistic DisorderSmilingAdolescentChildFemaleHumansMaleSex FactorsSocial Interactionautismcomputer visionfacial expressionsex differencessmiling

Identifiers

PMID39560147
PMCPMC12040582

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.