Evidence map›Paper›PMID 39559964›Full record

ReviewCancer reports (Hoboken, N.J.)2024

Crosstalk Between the Intratumoral Microbiota and the Tumor Microenvironment: New Frontiers in Solid Tumor Progression and Treatment.

Qing Zhou, Lijun Zhou, Xi Chen, Qiuyan Chen, Lu Hao

Abstract readReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. The authors respond to feedback onFrontiers in oncology · 2026
    Article
  4. Article
  5. [Research Progress on the Relationship between Intratumor Microbiota and Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025
    Review
  6. Multiomics profiling reveals thatFrontiers in cellular and infection microbiology · 2025
    Article
  7. Review
  8. Emerging technologies and current challenges in intratumoral microbiota research.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qing ZhouCentral Laboratory, The People's Hospital of Baoan Shenzhen, Shenzhen, China.
Lijun ZhouDepartment of Urology, The People's Hospital of Baoan Shenzhen, Shenzhen, China.
Xi ChenCentral Laboratory, The People's Hospital of Baoan Shenzhen, Shenzhen, China.
Qiuyan ChenScience and Education Department, Shenzhen Baoan Shiyan People's Hospital, Shenzhen, China.
Lu HaoScience and Education Department, Shenzhen Baoan Shiyan People's Hospital, Shenzhen, China.ORCID 0000-0002-4305-7766

Funding

Health and Medical Scientific Research Project of Shenzhen Bao'an Medical Association BAYXH2023026
6 · The paper itself

Abstract

backgroundThe microbiota plays a significant role in the tumor microenvironment, and its impact on tumor development and treatment outcome cannot be overlooked. Thus, it is essential to comprehend the interactions between the microbiota and the tumor microenvironment. RECENT

findingsWith the advent of next-generation sequencing, microbiota research has advanced significantly in recent years. The interaction between the intratumoral microbiota and the tumor microenvironment is an emerging area of research that holds great promise for understanding and treating solid tumor progression. This crosstalk between the intratumoral microbiota and the tumor microenvironment is a complex process that involves a multitude of factors, including the immune system, cellular signaling pathways, and metabolic processes. The origin of the intratumoral microbiota differs between various solid tumor, and the quantity and diversity of intratumoral microbiota also fluctuate significantly within each solid tumor.

conclusionThe aim of this review is to provide a detailed summary of the intratumoral microbiota in various types of solid tumors. This will include an analysis of their origins, differences, and how they impact the progression of solid tumors. Furthermore, we will emphasize the significant potential that the intratumoral microbiota holds for the diagnosis and treatment of solid tumors.

Indexed as

Disease ProgressionMicrobiotaNeoplasmsTumor MicroenvironmentAnimalsHumansintratumoral microbiotaoriginsprogressionsolid tumorstreatment

Identifiers

PMID39559964
PMCPMC11574561

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.