ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
A Fully Integrated Orthodontic Aligner With Force Sensing Ability for Machine Learning-Assisted Diagnosis.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- A Dopamine Driven Dual-Amplifier Strategy for High Performance Bioorganic Piezoelectrics via Secondary-Structure Modulation and Synergistic Molecular Dipoles.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Mechanobiology of orofacial tissues: principles, mechanisms, and therapeutic applications.International journal of oral science · 2026Review
- Artificial Intelligence in the Design and Optimization of Orthodontic Materials: A Clinical Perspective on Current State and Future Directions.Materials (Basel, Switzerland) · 2026Article
- Current Status and Future Perspectives of Wearable Technologies for Oral Health in Clinical Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Present and Future of the Use of Artificial Intelligence in Orthodontics.Bioengineering (Basel, Switzerland) · 2026Review
- Biosensors in dental, oral and craniofacial applications.Npj biosensing · 2026Review
- The Expanding Role of Artificial Intelligence in Dentistry: A Cross-Specialty Chairside Perspective.Cureus · 2025Review
- All-In-One Iontronic Sensing Aligner for High-Precision 3D Orthodontic Force Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Applications of artificial intelligence in diagnosis and treatment planning of orthodontics: a narrative review.The Saudi dental journal · 2025Review
- A Fully Integrated Orthodontic Aligner With Force Sensing Ability for Machine Learning-Assisted Diagnosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Currently, the diagnosis of malocclusion is a highly demanding process involving complicated examinations of the dental occlusion, which increases the demand for innovative tools for occlusal data monitoring. Nevertheless, continuous wireless monitoring within the oral cavity is challenging due to limitations in sampling and device size. In this study, by embedding high-performance piezoelectric sensors into the occlusal surfaces using flexible printed circuits, a fully integrated, flexible, and self-contained transparent aligner is developed. This aligner exhibits excellent sensitivity for occlusal force detection, with a broad detection threshold and continuous pressure monitoring ability at eight distinct sites. Integrated with machine learning algorithm, this fully integrated aligner can also identify and track adverse oral habits that can cause/exacerbate malocclusion, such as lip biting, thumb sucking, and teeth grinding. This system achieved 95% accuracy in determining malocclusion types by analyzing occlusal data from over 1400 malocclusion models. This fully-integrated sensing system, with wireless monitoring and machine learning processing, marks a significant advancement in the development of intraoral wearable sensors. Moreover, it can also facilitate remote orthodontic monitoring and evaluation, offering a new avenue for effective orthodontic care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.