Evidence map›Paper›PMID 39559697›Full record

ArticleClinical and translational radiation oncology2025

Clinical implementation of RTT-only CBCT-guided online adaptive focal radiotherapy for bladder cancer.

K Goudschaal, S Azzarouali, J Visser, M Admiraal, J Wiersma, N van Wieringen, A de la Fuente, M Piet, L Daniels, D den Boer and 2 more

Abstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The Unseen Pillars of Precision: A Qualitative Study on Feedback, Communication, and Motivation Among Medical Technologists in Radiation Oncology.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  3. Article
  4. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

K GoudschaalAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Meibergdreef 9, Amsterdam, the Netherlands.
S AzzaroualiAmsterdam UMC Location Vrije Universiteit Amsterdam, Radiation Oncology, De Boelelaan 1117, Amsterdam, the Netherlands.
J VisserAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Meibergdreef 9, Amsterdam, the Netherlands.
M AdmiraalAmsterdam UMC Location Vrije Universiteit Amsterdam, Radiation Oncology, De Boelelaan 1117, Amsterdam, the Netherlands.
J WiersmaAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Meibergdreef 9, Amsterdam, the Netherlands.
N van WieringenAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Meibergdreef 9, Amsterdam, the Netherlands.
A de la FuenteAmsterdam UMC Location Vrije Universiteit Amsterdam, Radiation Oncology, De Boelelaan 1117, Amsterdam, the Netherlands.
M PietAmsterdam UMC Location Vrije Universiteit Amsterdam, Radiation Oncology, De Boelelaan 1117, Amsterdam, the Netherlands.
L DanielsAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Meibergdreef 9, Amsterdam, the Netherlands.
D den BoerAmsterdam UMC Location Vrije Universiteit Amsterdam, Radiation Oncology, De Boelelaan 1117, Amsterdam, the Netherlands.
M HulshofAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Meibergdreef 9, Amsterdam, the Netherlands.
A BelAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Meibergdreef 9, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The study assesses the clinical implementation of radiation therapist (RTT)-only Conebeam CT (CBCT)-guided online adaptive focal radiotherapy (oART) for bladder cancer, by describing the training program, analyzing the workflow and monitoring patient experience. Materials and methods: Bladder cancer patients underwent treatment (20 sessions) on a ring-based linac (Ethos, Varian, a Siemens Healthineers Company, USA). Commencing April 2021, 14 patients were treated by RTTs supervised by the Radiation Oncologist (RO) and Medical Physics Expert (MPE) in a multidisciplinary workflow. From March 2022, 14 patients were treated solely by RTTs. RTT training included target delineation lessons and practicing oART in a simulation environment. We analyzed the efficiency of the RTT-only workflow regarding session time, adjustments by RTTs, attendance of the RO and MPE at the linac, and qualitative assessment of gross tumor volume (GTV) delineation. Patient experience was monitored through questionnaires. Results: A training program resulted in a skilled team of RTTs, ROs and MPEs.The RTT-only workflow demonstrated shorter session times compared to the multidisciplinary approach. Among 14 patients treated using the RTT-only workflow, RTTs adjusted 99% of bladder volumes and 44% of GTV. 79% of the sessions proceeded without MPEs and ROs. All GTV delineations were RO-approved, thus considered clinically acceptable, and 87% required minor or no adjustments. Patient satisfaction was reported in 18 of 21 cases. Conclusions: The RTT-only oART workflow for bladder cancer, complemented by a training program and on-call support from ROs and MPEs, demonstrated success. Patient experience is positive. It is currently introduced as standard in our clinic.

Indexed as

Bladder cancerBladder sparing treatmentCBCT-guided RTT-only workflowOnline adaptive focal radiotherapyRTT-only

Identifiers

PMID39559697
PMCPMC11570400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.