ArticleCureus2024
Relationship Between Osteoarthritis and Postmenopausal Osteoporosis: An Analysis Based on the National Health and Nutrition Examination Survey.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- The association between body mass index and osteoporosis, with consideration of sex differences: a systematic review and dose-response meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Due to the increased prevalence of osteoarthritis (OA) and osteoporosis (OP) in women, urgent interventions are needed to reduce the risk of postmenopausal fractures in female OA patients. Moreover, the relationship between OA and OP remains contentious, emphasizing the need for further research to deepen our understanding. This study aimed to investigate the relationship between OA and postmenopausal OP using data from the National Health and Nutrition Examination Survey (NHANES). Methods We conducted a cross-sectional analysis using NHANES summary data from 2005 to 2010, 2013 to 2014, and 2017 to 2020. Multivariable logistic regression was employed to evaluate the association between OA and the risk of postmenopausal OP. Adjustments were made for potential confounding factors. Additionally, we conducted stratified analyses, which provided further insights into the association between OA and postmenopausal OP across various subgroups. Results The analysis revealed a significant correlation between OA and an increased risk of postmenopausal OP, with an odds ratio (OR) of 1.12 (95% confidence interval (CI): 1.07-1.17, P < 0.001) after adjusting for confounders. Stratified analyses revealed a significant association between OA and postmenopausal OP in obese and overweight individuals (OR 1.14, 95% CI 1.06-1.22, P < 0.001; OR 1.18, 95% CI 1.04-1.32, P = 0.008) and among former or current smokers (OR 1.20, 95% CI 1.08-1.33, P < 0.001). Conclusions The study underscores a significant association between OA and postmenopausal OP, particularly in obese, overweight, and smoking populations. Given the higher prevalence of OA and OP among women, understanding these associations could lead to improved strategies for reducing postmenopausal fracture risks. The study offers valuable insights and potential directions for future therapeutic approaches.
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