Evidence map›Paper›PMID 39559574›Full record

ArticleRSC advances2024

Selenenylsulfide covalent-directed chemistry for the detection of sulfhydryl groups using a diselenide fluorescent probe.

Chunqiu Ma, Jichao Xu, Xiaolu Wang, Xuewen Wang, Lei Zhang, Su Jing

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chunqiu MaSchool of Chemistry and Molecular Engineering, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 Jiangsu China sjing@njtech.edu.cn.
Jichao XuSchool of Chemistry and Molecular Engineering, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 Jiangsu China sjing@njtech.edu.cn.
Xiaolu WangSchool of Chemistry and Molecular Engineering, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 Jiangsu China sjing@njtech.edu.cn.
Xuewen WangSchool of Chemistry and Molecular Engineering, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 Jiangsu China sjing@njtech.edu.cn.
Lei ZhangSchool of Chemistry and Molecular Engineering, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 Jiangsu China sjing@njtech.edu.cn.
Su JingSchool of Chemistry and Molecular Engineering, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 Jiangsu China sjing@njtech.edu.cn.ORCID https://orcid.org/0000-0002-8520-1084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the development of a diglycosyldiselenide-based fluorescent probe for the rapid detection of sulfhydryl-containing biomolecules. The probe facilitates a chemoselective coupling reaction with sulfhydryl groups in aqueous buffer under ambient conditions, resulting in the formation of homogeneous Se-S conjugates within one hour. Using glutathione, a sulfhydryl-containing biomolecule, as a proof of concept, the probe achieved a detection limit of 0.75 μM based on the 3

Identifiers

PMID39559574
PMCPMC11571120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.