Evidence map›Paper›PMID 39559532›Full record

ArticleEuropean urology open science2024

Flexible Ureteroscopy with a Tip-bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3-cm Renal Stones: Study Protocol for an International, Multicenter, Randomized, Parallel-group, Noninferiority Trial.

Wei Zhu, Chu Ann Chai, Jinxiang Ma, Mehmet İlker Gökce, Nariman Gadzhiev, Jaisukh Kalathia, Kehua Jiang, Xianzhong Duan, Jianwei Cao, Rongpei Wu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European urology open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wei ZhuDepartment of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Chu Ann ChaiDepartment of Urology, University Malaya Medical Centre, Kuala Lumpur, Malaysia.
Jinxiang MaSchool of Public Health, Guangzhou Medical University, Guangzhou, China.
Mehmet İlker GökceDepartment of Urology, School of Medicine, Ankara University, Ankara, Turkey.
Nariman GadzhievDepartment of Urology, St. Petersburg State University Hospital, St. Petersburg, Russia.
Jaisukh KalathiaDepartment of Urology and Kidney Transplantation, Fortune Urology Clinic, Gujarat, India.
Kehua JiangDepartment of Urology, Guizhou Provincial People's Hospital, Guizhou, China.
Xianzhong DuanDepartment of Urology, Baoshan No. 2 People's Hospital, Baoshan, China.
Jianwei CaoXinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Rongpei WuDepartment of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Rijin SongDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Song BaiDepartment of Urology, Shengjing Hospital, China Medical University, Shenyang, China.
Xuedong LiDepartment of Urology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Shusheng LiuDepartment of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Guohua ZengDepartment of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guidelines recommend percutaneous nephrolithotomy (PCNL) for larger renal stones, but advances in flexible ureteroscopy (f-URS) with a tip-bendable suction ureteral access sheath (S-UAS) have prompted further investigation. Our multicenter, international, randomized controlled trial is investigating whether f-URS with S-UAS is noninferior to mini-PCNL (mPCNL) for renal stones of 2-3 cm. The primary objective is the immediate stone-free rate (SFR). Secondary outcomes include the 3-mo SFR, complication rates, surgical time, hospital stay, auxiliary procedures, and improvements in quality of life. A total of 720 patients from 12 urological centers will be randomized to either f-URS with S-UAS or PCNL. Statistical analyses will include intention-to-treat and per-protocol approaches, with specific methods for normally and non-normally distributed data. Subgroup analyses will focus on stone location and lithotripter types. The significance threshold will be set at

Indexed as

Flexible urteroscopyPercutaneous nephrolithotomyRetrograde intrarenal surgeryTip bandable suction ureteral access sheathUreteral access sheathUrolithiasis

Identifiers

PMID39559532
PMCPMC11570736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.