Evidence map›Paper›PMID 39559423›Full record

ArticleBioactive materials2025

Engineered nanoplatform mediated gas therapy enhanced ferroptosis for tumor therapy

Kun Xu, Ke Li, Ye He, Yulan Mao, Xuan Li, Liangshuai Zhang, Meijun Tan, Yulu Yang, Zhong Luo, Peng Liu and 1 more

Abstract read
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kun XuKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Ke LiKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Ye HeThomas Lord Department of Mechanical Engineered and Materials Science, Duke University, Durham, NC, 27708, USA.
Yulan MaoKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Xuan LiKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Liangshuai ZhangKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Meijun TanKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Yulu YangKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Zhong LuoSchool of Life Science, Chongqing University, Chongqing, 400044, PR China.
Peng LiuKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.
Kaiyong CaiKey Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineered, Chongqing University Chongqing, 400044, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high glutathione (GSH) environment poses a significant challenge for inducing ferroptosis in tumor cells, necessitating the development of nanoplatforms that can deplete intracellular GSH. In this study, we developed an engineered nanoplatform (MIL-100@Era/L-Arg-HA) that enhances ferroptosis through gas therapy. First, we confirmed that the Fe element in the nanoplatform undergoes valence changes under the influence of high GSH and H

Indexed as

FerroptosisGas therapyGSHNO

Identifiers

PMID39559423
PMCPMC11570688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.