Evidence map›Paper›PMID 39559211›Full record

ArticleHeliyon2024

Relative fitness of wild-type and phage-resistant pyomelanogenic

Aarcha Shanmugha Mary, Nashath Kalangadan, John Prakash, Srivignesh Sundaresan, Sutharsan Govindarajan, Kaushik Rajaram

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Giving Antibiotics a Second Chance: Evolutionary Trade-Offs and Phage-Driven Restoration of Antibiotic Susceptibility.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aarcha Shanmugha MaryDepartment of Microbiology, Central University of Tamil Nadu, Thiruvarur, Tamil Nadu, India.
Nashath KalangadanDepartment of Microbiology, Central University of Tamil Nadu, Thiruvarur, Tamil Nadu, India.
John PrakashDepartment of Chemistry, Central University of Tamil Nadu, Thiruvarur, Tamil Nadu, India.
Srivignesh SundaresanDepartment of Horticulture, Central University of Tamil Nadu, Thiruvarur, Tamil Nadu, India.
Sutharsan GovindarajanDepartment of Biological Sciences, SRM University, AP, Amaravati, 522240, Andhra Pradesh, India.
Kaushik RajaramDepartment of Microbiology, Central University of Tamil Nadu, Thiruvarur, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophages, the natural predators of bacteria, are incredibly potent candidates to counteract antimicrobial resistance (AMR). However, the rapid development of phage-resistant mutants challenges the potential of phage therapy. Understanding the mechanisms of bacterial adaptations to phage predation is crucial for phage-based prognostic applications. Phage cocktails and combinatorial therapy, using optimized dosage patterns of antibiotics, can negate the development of phage-resistant mutations and prolong therapeutic efficacy. In this study, we describe the characterization of a novel bacteriophage and the physiology of phage-resistant mutant developed during infection. M12PA is a

Indexed as

AntibioticsAntimicrobial resistanceAnti-phage mutationPhage cocktailsPigmentsPyomelanin

Identifiers

PMID39559211
PMCPMC11570307

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.