ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2024
Neoteric Predictors for Lymph Node Metastasis in Early Oral Squamous Cell Carcinoma: Tumor Budding and Worst Pattern of Invasion.
Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Prognostic Role of Worst Pattern of Invasion in Oral Squamous Cell Carcinoma.Journal of clinical medicine · 2026Review
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7 authors.
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Abstract
Oral cancer is one of the most common cancers seen in the Indian subcontinent. Its primary treatment is surgery with or without adjuvant treatment. Despite advances in science, prognosis and overall survival has not yet chanced over the past two decades. Pathologically proven regional lymph node metastasis adversely affects the prognosis. This study was conducted to evaluate the predictive factors for lymph node metastasis in Stage I and II oral squamous cell carcinoma (OSCC) with distinct emphasis on tumor budding and worst pattern of invasion. This is a prospective observational study was done at a tertiary care center, Prince Aly Khan Hospital, Mumbai, over a period of 22 months (March, 2020 to December, 2021). We analyzed 237 patients of early OSCC for clinicopathological parameters (age, trismus, differentiation, depth of invasion, tumor budding, worst pattern of invasion). Chi Square test and logistic regression model were used for data evaluation. Statistical Package for Social Sciences, version 21.0 IBM Corporation USA for Microsoft Windows, was used for data analysis. This study reported statistically significant predictive factors for lymph node metastasis viz. tumor budding (OR 30.8 95% CI 12.365-76.731
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