Auto-Gait: Automatic Ataxia Risk Assessment with Computer Vision on Gait Task Videos.

Many patients with neurological disorders, such as Ataxia, do not have easy access to neurologists, -especially those living in remote localities and developing/underdeveloped countries. Ataxia is a degenerative disease of the nervous system that surfaces as difficulty with motor control, such as walking imbalance. Previous studies have attempted automatic diagnosis of Ataxia with the help of wearable biomarkers, Kinect, and other sensors. These sensors, while accurate, do not scale efficiently well to naturalistic deployment settings. In this study, we propose a method for identifying ataxic symptoms by analyzing videos of participants walking down a hallway, captured with a standard monocular camera. In a collaboration with 11 medical sites located in 8 different states across the United States, we collected a dataset of 155 videos along with their severity rating from 89 participants (24 controls and 65 diagnosed with or are pre-manifest spinocerebellar ataxias). The participants performed the gait task of the Scale for the Assessment and Rating of Ataxia (SARA). We develop a computer vision pipeline to detect, track, and separate the participants from their surroundings and construct several features from their body pose coordinates to capture gait characteristics such as step width, step length, swing, stability, speed, etc. Our system is able to identify and track a patient in complex scenarios. For example, if there are multiple people present in the video or an interruption from a passerby. Our Ataxia risk-prediction model achieves 83.06% accuracy and an 80.23% F1 score. Similarly, our Ataxia severity-assessment model achieves a mean absolute error (MAE) score of 0.6225 and a Pearson's correlation coefficient score of 0.7268. Our model competitively performed when evaluated on data from medical sites not used during training. Through feature importance analysis, we found that our models associate wider steps, decreased walking speed, and increased instability with greater Ataxia severity, which is consistent with previously established clinical knowledge. Furthermore, we are releasing the models and the body-pose coordinate dataset to the research community - the largest dataset on ataxic gait (to our knowledge). Our models could contribute to improving health access by enabling remote Ataxia assessment in non-clinical settings without requiring any sensors or special cameras. Our dataset will help the computer science community to analyze different characteristics of Ataxia and to develop better algorithms for diagnosing other movement disorders.