Evidence map›Paper›PMID 39558881›Full record

ReviewCancer medicine2024

Advances in the Understanding of the Pathogenesis of Triple-Negative Breast Cancer.

Yuhan Liu, Yuhan Zou, Yangli Ye, Yong Chen

Abstract readReview
In one paragraph

Review in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuhan LiuSchool of Clinical Medicine, Shandong Second Medical University, Weifang, China.ORCID https://orcid.org/0009-0004-2289-9691
Yuhan ZouSchool of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Yangli YeCollege of Life Sciences and Technology, Shandong Second Medical University, Weifang, China.
Yong ChenKey Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang, China.

Funding

Innovation and Entrepreneurship Training Program for University Students of Shandong Second Medical University X2023409National Natural Science Foundation of China 81303198
6 · The paper itself

Abstract

backgroundTriple-negative breast cancer (TNBC) is a heterogeneous disease characterized by high aggressiveness, high malignancy, and poor prognosis compared to other breast cancer subtypes.

objectiveThis review aims to explore recent advances in understanding TNBC and to provide new insights and potential references for clinical treatment.

methodsWe examined current literature on TNBC to analyze molecular subtypes, genetic mutations, signaling pathways, mechanisms of drug resistance, and emerging therapies.

resultsFindings highlight key aspects of TNBC's molecular subtypes, relevant mutations, and pathways, alongside emerging treatments that target drug resistance mechanisms.

conclusionThese insights into TNBC pathogenesis may help guide future therapeutic strategies and improve clinical outcomes for patients with TNBC.

Indexed as

Drug Resistance, NeoplasmMutationSignal TransductionTriple Negative Breast NeoplasmsBiomarkers, TumorFemaleHumansMolecular Targeted TherapyPrognosisBiomarkers, Tumorclassificationdrug resistancegenomic alterationssignaling pathwaystriple‐negative breast cancer

Identifiers

PMID39558881
PMCPMC11574469

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.