Evidence map›Paper›PMID 39558749›Full record

ArticlePediatrics2024

Sleep-Related Sudden Unexpected Infant Death Among Infants Prenatally Substance Exposed.

Stephanie Anne Deutsch, Claire E Loiselle, Jobayer Hossain, Allan De Jong

Abstract read
In one paragraph

Article in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Stephanie Anne DeutschDepartment of Pediatrics, Nemours Children's Health, Delaware, Wilmington, Delaware.
Claire E LoiselleNemours Biomedical Research, Wilmington, Delaware.
Jobayer HossainBiostatistics Program, Nemours Biomedical Research, Nemours Children's Health, Delaware, Wilmington, Delaware.
Allan De JongDepartment of Pediatrics, Nemours Children's Health, Delaware, Wilmington, Delaware.

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Megan M Wenner · 2013 to 2026
$60.5M
NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

BACKGROUND AND

objectivesMaternal substance use during pregnancy heightens risk of sudden unexpected infant death (SUID), including through unsafe sleep practices. Families impacted by substance use frequently experience disproportionate social drivers of poor health and family vulnerability likely contributory to fatality risk. Characteristics of sleep-related SUID among infants born prenatally substance exposed versus nonexposed were compared to identify targeted prevention opportunities.

methodsUsing the Sudden Death in the Young Registry, we examined SUID with sleep-related death between 2015 and 2020 across infants prenatally exposed versus nonexposed. Distribution of sleep environment characteristics, social drivers of poor health, and family vulnerability factors were examined using descriptive statistics and χ2.

resultsOf 2010 infants who experienced sleep-related deaths, 283 (14%) were prenatally exposed. More than half of deaths involved an adult bed (52%, n = 1045) or surface sharing with an adult (53%, n = 1074). Supervisors of prenatally exposed infants were disproportionately impaired at infant death versus nonexposed (34%, n = 97 vs 16%, n = 279). Statistically significant associations between prenatal exposure history and vulnerability factors (insurance, child welfare involvement, intimate partner violence, health care barriers) were identified (P < .05).

conclusionsSleep-related SUID across infants prenatally exposed versus nonexposed differ in sleep environment characteristics and contributory social vulnerability. Disproportionate sleep environment hazards (surface sharing, supervisor impairment) are identified among prenatally exposed infants that should compel targeted prevention efforts, including safe sleep messaging, discouraging surface sharing, and engaging support persons during impairment periods. Addressing social needs and family vulnerability are also paramount to increase access to health care, safe sleep education, and material resource provision.

Indexed as

Prenatal Exposure Delayed EffectsSubstance-Related DisordersSudden Infant DeathAdultFemaleHumansInfantInfant, NewbornMalePregnancyRegistriesRisk FactorsSleep

Identifiers

PMID39558749
PMCPMC11614156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.