ReviewJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2025
Advances in Dental Restorations: A Comprehensive Review of Machinable and 3D-Printed Ceramic-Reinforced Composites.
Review in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07429747 (Performance of Reinforced 3D-Printed Versus Direct Bulk-Filled Resin Composites for Restoring Extensive Class II Cavities in Vital Molars), which is not on this map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Performance of Reinforced 3D-Printed Versus Direct Bulk-Filled Resin Composites for Restoring Extensive Class II Cavities in Vital Molars: A Randomized Clinical Trial
Who cites it
33 citing papers in PubMed.
- Article
- Mechanical performance and color stability of 3D-printed ceramic-filled resin following various bleaching regimens: an in vitro study.BMC oral health · 2026Article
- Comparative Quasi-Static Compressive Loading Performance of Two Ultrathin Ceramic Occlusal Veneers for Minimally Invasive Restorations.Biomimetics (Basel, Switzerland) · 2026Article
- Influence of printing orientation on the mechanical and surface characteristics of a novel 3D-printed definitive resin-based composite.Odontology · 2026Article
- Fracture Resistance of 3D-Printed Partial and Conventional Veneers.Journal of functional biomaterials · 2026Article
- Size-Dependent Strength and Reliability of Resin Composite Blocks and Nanoceramics for Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Restorations.Materials (Basel, Switzerland) · 2026Article
- Repair Performance of Additively and Subtractively Manufactured Permanent Crown Materials: A Combined Mechanical and Optical Evaluation.Materials (Basel, Switzerland) · 2026Article
- From bone replacement to regeneration. A biomaterials started journey.Materials today. Bio · 2026Review
- From polyetheretherketone to 3D‑printed composites: hydrothermal stability and cement‑dependent resin bonding of high‑performance polymers to pediatric restorations.BMC oral health · 2026Article
- Article
- Article
- Effect of preparation design on the fracture behavior of 3D-printed restorations in an in-vitro tooth wear model.BMC oral health · 2026Article
- Review
- A Review of Current Systems, Materials, and Protocols for 3D-Printed Splints, Crowns, and Dentures.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Review
- Additive manufacturing for Dentistry: A comprehensive review of techniques and applications.Progress in materials science · 2026Article
- Surface Characteristics and Hydrolytic Stability in Milled and 3D-Printed PMMA Dental Materials.Polymers · 2026Article
- Fracture resistance of endocrowns produced by 3D printing and CAD-CAM blocks: a comparative assessment.Clinical oral investigations · 2026Article
- Effect of in-office bleaching on surface roughness of additively versus subtractively manufactured tooth-colored materials used for fixed definitive prostheses.BMC oral health · 2026Article
- Influence of repetitive diamond bur use on the trueness and surface roughness of subtractively manufactured PICN restorations.Biomaterial investigations in dentistry · 2026Article
- Fractographic analysis of 3D printed hybrid ceramic single crowns with different aging and post-curing times: an in-vitro study.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis review aims to evaluate the current understanding and clinical applications of machinable ceramic-reinforced composites (CRCs) and the emerging first generation of 3D-printed CRCs in dental restorations. OVERVIEW: Machinable CRCs, introduced over a decade ago, have shown moderate success in short- to medium-term clinical applications, particularly in low-stress areas. However, their long-term durability limitations, such as increased wear and marginal deterioration, restrict their use in high-stress situations and full crowns. The first generation of 3D-printed CRCs offers customization advantages but is still in early development and exhibits lower mechanical strength and higher wear rates than CAD-CAM CRCs and traditional ceramics. Additionally, the classification and definitions surrounding CRCs remain ambiguous, as ADA categorizations do not clearly differentiate CRCs from ceramics, complicating clinical indication, usage, and billing practices.
conclusionMachinable CAD-CAM CRCs are moderately successful in low-stress applications, while 3D-printed CRCs show limitations in wear resistance and durability, raising concerns for their use in definitive restorations. Both require further research and clinical validation. CLINICAL SIGNIFICANCE: Machinable CAD-CAM CRCs are best suited for low-stress applications, while 3D-printed CRCs may be more appropriate for provisional use. Until long-term clinical data are available, ceramics should be preferred for high-stress or full-coverage restorations. Clearer definitions for porcelain/ceramic and comprehensive application guidelines are urgently needed to support clinician decision-making and improve patient outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.