Evidence map›Paper›PMID 39558296›Full record

ArticleBMC public health2024

Undiagnosed hypertension and diabetes mellitus in the Tabari cohort: a population-based study.

Mahmood Moosazadeh, Pedram Ebrahimnejad, Mehrnoush Sohrab, Alireza Rafiei, Mahdi Abastabar, Maryam Khazaee-Pool, Shamim Mahboubi, Motahareh Kheradmand

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Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mahmood MoosazadehGastrointestinal Cancer Research Center, Non- Communicable Diseases Research Institute, Mazandaran University of Medical Sciences, Mazandaran, Iran.
Pedram EbrahimnejadDepartment of Pharmaceutics, Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Mehrnoush SohrabDepartment of Internal Medicine, Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Alireza RafieiDepartment of Immunology, School of Medicine, Molecular and Cell Biology Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Mazandaran, Iran.
Mahdi AbastabarDepartment of Medical Mycology, School of Medicine, Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Maryam Khazaee-PoolDepartment of Public Health, School of Health, Health Sciences Research Center, Associate Professor of Health Education and Promotion, Mazandaran University of Medical Sciences, Sari, Iran.
Shamim MahboubiDeputy of Research and Technology, Mazandaran University of Medical Sciences, Sari, Iran.
Motahareh KheradmandHealth Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran. elham.kherad@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUndiagnosed hypertension (HTN) and diabetes mellitus (DM) are major public health challenges worldwide. We aimed to investigate the prevalence of undiagnosed HTN and DM, and their correlates, in a large-scale population-based cohort study.

methodsIn this cross-sectional study, data collected during the enrollment phase of the Tabari Cohort study (TCS) were utilized. Data were collected in the TCS using a standard questionnaire, blood collection, and measurement of anthropometric indices and blood pressure. Data were analyzed using the chi-squared test and univariate and multivariate logistic regression analyses. Undiagnosed HTN included those who were not aware of HTN at the time of enrollment but had systolic and diastolic blood pressures ≥ 140 mm or ≥ 90 mmHg, respectively. Undiagnosed DM included participants who were unaware of their DM at the time of enrollment and had FBS levels ≥ 126 mg/dL.

resultsThe total prevalence of undiagnosed HTN and DM were 5% (508) and 4.7% (485), respectively. The findings of multivariable logistic regression analysis showed that young age (OR: 0.40, P < 0.001), residents of urban regions (OR: 0.70, P = 0.03), lower Body Mass Index kg/m2 (BMI) (OR: 0.51, P = 0.002), waist-to-hip ratio (WHR)(OR: 0.70, P = 0.023), total cholesterol (TC) ≥ 200 mg/dL (OR: 0.1.83, P < 0.001), lack of history of DM (OR: 0.38,P < 0.001), cardiovascular diseases (CVD)(OR: 0.12, P < 0.001), and lack of a positive family history of HTN in first-(OR: 0.39, P < 0.001) and second-degree(OR: 0.56, P = 0.009) relatives were the main predictors of undiagnosed HTN. Accordingly, male sex(OR: 0.52, P = 0.004), young age(OR: 0.28, P < 0.001), residence in urban regions(OR: 0.30, P < 0.001), BMI ≥ 30 (OR: 1.51, P = 0.044), low-density lipoprotein (LDL) ≥ 130 mg/dL (OR:1.93, P < 0.001), TC ≥ 200 mg/dL (95% CI, 1.47-2.51, P < 0.001), positive history of chronic kidney disease (OR:1.39, P = 0.010 ), and lack of family history of first-(OR: 0.38, P < 0.001) and second-degree (OR: 0.62, P < 0.015) DM were the main predictors of undiagnosed DM.

conclusionOverall, younger participants, those residing in urban areas, those with TC ≥ 200 mg/dL, and those without a positive family history of HTN or DM were at a greater risk of undiagnosed HTN/DM.

Indexed as

Diabetes MellitusHypertensionAdultAgedCohort StudiesCross-Sectional StudiesFemaleHumansIranMaleMiddle AgedPrevalenceRisk FactorsUndiagnosed DiseasesPrevalenceTabari cohort populationUndiagnosed diabetes mellitusUndiagnosed hypertension

Identifiers

PMID39558296
PMCPMC11571944

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.