Evidence map›Paper›PMID 39558271›Full record

ArticleBMC neuroscience2024

Does choline have an effect on Transient Global Amnesia (TGA)?

Sasan Rahmanian, Mahsa Shapouri, Mohammad Keshavarz Mohammadian, Zahra Mahmoudi, Zahra Saeedirad, Khadijeh Abbasi Mobarakeh, Abdolrahman Parhiz, Soheila Shekari, Asma Rajabi Harsini, Neda Valisoltani and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Choline-An Essential Nutrient with Health Benefits and a Signaling Molecule.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sasan RahmanianNursing Faculty, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahsa ShapouriShahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad Keshavarz MohammadianDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Zahra MahmoudiDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Zahra SaeediradDepartment of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Khadijeh Abbasi MobarakehNutrition and Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Abdolrahman ParhizKish International Campus, University of Tehran, Tehran, Iran.
Soheila ShekariDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Asma Rajabi HarsiniDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Neda ValisoltaniDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Sara KhoshdoozFaculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Saeid DoaeiDepartment of Community Nutrition, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, School of Nutrition and Food Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Doaei@gums.ac.ir.
Akram KooshkiNon-Communicable Diseases Research Center, Department of Nutrition and Biochemistry, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran. Kooshki555@gmail.com.
Maryam GholamalizadehCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

Sabzevar University of Medical Sciences,Iran 74865
6 · The paper itself

Abstract

backgroundCholine was frequently reported to have some beneficial effects on memory function. However, the association of dietary choline with different types of amnesia is not well understood. The objective of this study was to examine the association between dietary intake of choline and transient global amnesia (TGA).

methodsThis case-control study was carried out on 258 patients with TGA and 520 participants without amnesia. Data on dietary choline intake was collected using a validated food frequency questionnaire (FFQ). All participants were examined for amnesia by a neurologist according to the Kaplan and Hodges criteria.

resultsThere was an inverse association between TGA and dietary choline intake after adjustment for age and gender (OR: 0.98, CI 95% 0.96-0.98, P = 0.03). The association remained significant after additional adjusting for physical activity, body mass index (BMI), occupation, marital status, smoking, and drinking alcohol (OR: 0.98, CI 95% 0.96-0.99, P = 0.04) and after further adjustment for calorie and food groups intake (OR: 0.98, CI 95% 0.96-0.99, P = 0.03).

conclusionThe results of this study indicated that choline may have beneficial effects against TGA. Further longitudinal studies are warranted.

Indexed as

Amnesia, Transient GlobalCholineAgedCase-Control StudiesDietFemaleHumansMaleMiddle AgedCholineCholineDietary intakeTransient Global Amnesia

Identifiers

PMID39558271
PMCPMC11575108

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.