Evidence map›Paper›PMID 39558228›Full record

ArticleBMC musculoskeletal disorders2024

Spinal navigation with AI-driven 3D-reconstruction of fluoroscopy images: an ex-vivo feasibility study.

Dietmar Luchmann, Sascha Jecklin, Nicola A Cavalcanti, Christoph J Laux, Aidana Massalimova, Hooman Esfandiari, Mazda Farshad, Philipp Fürnstahl

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Beyond traditional orthopaedic data analysis: AI, multimodal models and continuous monitoring.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dietmar LuchmannResearch in Orthopedic Computer Science, Balgrist University Hospital, University of Zurich, Lengghalde 5, Zurich, 8008, Switzerland. dietmar.luchmann@uzh.ch.
Sascha JecklinResearch in Orthopedic Computer Science, Balgrist University Hospital, University of Zurich, Lengghalde 5, Zurich, 8008, Switzerland.
Nicola A CavalcantiResearch in Orthopedic Computer Science, Balgrist University Hospital, University of Zurich, Lengghalde 5, Zurich, 8008, Switzerland.
Christoph J LauxDepartment of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, 8008, Switzerland.
Aidana MassalimovaResearch in Orthopedic Computer Science, Balgrist University Hospital, University of Zurich, Lengghalde 5, Zurich, 8008, Switzerland.
Hooman EsfandiariResearch in Orthopedic Computer Science, Balgrist University Hospital, University of Zurich, Lengghalde 5, Zurich, 8008, Switzerland.
Mazda FarshadDepartment of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, 8008, Switzerland.
Philipp FürnstahlResearch in Orthopedic Computer Science, Balgrist University Hospital, University of Zurich, Lengghalde 5, Zurich, 8008, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the increasing number of surgeries utilizing spinal instrumentation, three-dimensional surgical navigation aims to improve the accuracy of implant placement. However, its widespread clinical adaption has been hindered by factors such as high radiation exposure and interference with standard surgical workflows.

methodsX23D is a novel AI-based fluoroscopy reconstruction technique that generates a 3D anatomical model of the spine from only four fluoroscopy images. Based on this technology, we developed a prototype for the surgical navigation of pedicle screws placement of the lumbar spine, visualizing the 3D-reconstructed spine anatomy and the surgical drill position in real-time. An ex-vivo study was conducted to compare the accuracy of the X23D-based navigation approach with fluoroscopy-aided freehand instrumentation. Five board-certified surgeons placed pedicle screws on six human torsi within a realistic surgical environment. Breach rate, site and extent (Gertzbein-Robbins) were evaluated in postoperative CT scans, as well as execution time, radiation dose, and user experience. Specimens, operating side, and surgeon were randomised.

resultsForty-nine pedicle screws (n = 24 × 23D, n = 25 2D-fluoroscopy) were evaluated, with six breaches occurring in the control group, one of which was considered clinically significant (medial breach grade C). Five breaches with one clinically significant breach were observed in the X23D group. Breach rate, execution time for each lumbar level (X23D 167 s vs. control 156 s), radiation dose (X23D 33.26 mGy vs. control 49.5 mGy), and user experience did not reveal significant differences (p > 0.05) between the groups.

conclusionsSpinal navigation using the X23D-based approach shows promise and performs well in a realistic surgical ex-vivo setting. With further refinements, its accuracy is expected to match clinical-grade navigation systems while reducing radiation dose.

Indexed as

Feasibility StudiesImaging, Three-DimensionalLumbar VertebraePedicle ScrewsArtificial IntelligenceFluoroscopyHumansModels, AnatomicSpinal FusionSurgery, Computer-AssistedTomography, X-Ray Computed3D-reconstructionArtificial intelligenceMachine learningPedicle screwSpine surgerySurgical navigationX23D

Identifiers

PMID39558228
PMCPMC11575073

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.