ArticleScientific reports2024
Reporting practices of anesthetic and analgesic use in rodent orthopedic research.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mechanically Induced Pulpitis: A Rat Model That Preserves Animal Well-Being.Biomedicines · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines, along with the updated ARRIVE 2.0, provide a crucial framework for transparent reporting in animal research. These guidelines enhance the quality and reproducibility of studies while supporting animal welfare. However, concerns persist regarding the reporting practices of biomedical researchers in scientific articles related to anesthesia and analgesia despite the endorsement of ARRIVE guidelines, as has been demonstrated in previous descriptive analyses. The current study systematically reviews articles published from 2016 to 2023 that involve rodent orthopedic surgeries. These procedures were selected as our focus given that anesthetics and analgesics are essential for such high impact procedures. We highlight significant reporting gaps, noting that anesthetic and analgesic details were missing in 29.4% and 74.8% of the articles, respectively. Our findings reveal no correlation between reporting completeness and journal impact factors, indicating that this issue generalized across journals. Furthermore, among articles that did report analgesia use, we observed a low prevalence of multimodal analgesia. Overall, this study underscores the urgent need to develop effective strategies to improve reporting of anesthesia and analgesia in animal studies to enhance ethical standards, animal welfare, and the robustness and reproducibility of research.
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Registered trials
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