ArticleNutrition & diabetes2024
Trends in Children's Dietary Inflammatory Index and association with prediabetes in U.S. adolescents.
Article in Nutrition & diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Inflammatory diet mediates the relationship between early life stress and inflammation in adolescents.Brain, behavior, and immunity · 2026Article
- The Natural History of Prediabetes and Cardiovascular Disease in the Pediatric Population.Biomedicines · 2026Review
- The "pro-inflammatory imprint" of ultra-processed food exposure: a review of mechanisms affecting child and adolescent health and development via the gut microbiome-inflammation axis.Frontiers in nutrition · 2026Review
- The relationship between sarcopenic obesity and prediabetes in adolescents: Analysis of the national health and nutrition examination survey from 2011 to 2016.Journal of clinical & translational endocrinology · 2025Article
- Adiposity indices mediate the association between dietary inflammatory index and type 2 diabetes risk in women with prior gestational diabetes mellitus.Diabetology & metabolic syndrome · 2025Article
- Editorial: The role of nutrition in pediatric chronic diseases: a focus on metabolic, genetic, and palliative care challenges.Frontiers in nutrition · 2025Article
- Non-linear relationship between the children's dietary inflammatory index and asthma risk: identifying a critical inflection point in US children and adolescents.Frontiers in nutrition · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesPrediabetes is a high-risk state for diabetes. We aimed to illustrate secular trends in the Children's Dietary Inflammation Index (C-DII) among U.S. adolescents and assess its association with prediabetes.
methodsAdolescents aged 12-18 years were collected from the National Health and Nutrition Examination Survey, 2001-2018. Prediabetes was defined based on Hemoglobin A1c, fasting glucose, and glucose tolerance levels. Risk was quantified by odds ratio (OR) and 95% confidence interval (CI).
resultsA total of 13,684 adolescents were analyzed, representing a weighted total population of 33,351,181. C-DII scores declined significantly from 2001 to 2012 and increased from 2013 to 2018. The relationship between C-DII and prediabetes was roughly linear. When assigning the low C-DII scores as the reference, adolescents with medium and high C-DII scores were 1.22 (adjusted 95% CI: 1.04-1.44) and 1.25 (0.99-1.60) times more likely to have prediabetes. In subgroup analyses, the risk for prediabetes was significantly enhanced in boys (adjusted OR = 1.26 and 1.45 for medium and high C-DII scores, 95% CI: 1.05-1.51 and 1.09-1.92), and in adolescents living in poor families for medium (1.34 and 1.44, 1.08-1.67 and 1.07-1.95).
conclusionsOur findings indicate a V-shaped secular trend in C-DII scores from 2001 to 2018 in U.S. adolescents, with the nadir in 2011-2012, and the risk for prediabetes was significantly increased by over 20% in adolescents possessing medium or high C-DII scores.
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