Evidence map›Paper›PMID 39557804›Full record

ReviewJournal of microbiology (Seoul, Korea)2024

Fecal Microbiota Transplantation: Indications, Methods, and Challenges.

Jee Young Lee, Yehwon Kim, Jiyoun Kim, Jiyeun Kate Kim

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Observational
  7. Microbiome Therapeutics for Clostridioides difficile Infection.Infectious disease clinics of North America · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jee Young LeeDepartment of Microbiology, Kosin University College of Medicine, Busan, 49267, Republic of Korea.
Yehwon KimDepartment of Medicine, Kosin University College of Medicine, Busan, 49267, Republic of Korea.
Jiyoun KimDepartment of Medicine, Kosin University College of Medicine, Busan, 49267, Republic of Korea.
Jiyeun Kate KimDepartment of Microbiology, Kosin University College of Medicine, Busan, 49267, Republic of Korea. kate.yi@kosin.ac.kr.ORCID http://orcid.org/0000-0002-0661-7410

Funding

National Research Foundation of Korea RS-2024-00340833
6 · The paper itself

Abstract

Over the past two decades, as the importance of gut microbiota to human health has become widely known, attempts have been made to treat diseases by correcting dysbiosis of gut microbiota through fecal microbiota transplantation (FMT). Apart from current knowledge of gut microbiota, FMT to treat disease has a long history, from the treatment of food poisoning in the fourth century to the treatment of Clostridioides difficile infections in the twentieth century. In 2013, FMT was recognized as a standard treatment for recurrent C. difficile because it consistently showed high efficacy. Though recurrent C. difficile is the only disease internationally recognized for FMT efficacy, FMT has been tested for other diseases and shown some promising preliminary results. Different FMT methods have been developed using various formulations and administration routes. Despite advances in FMT, some issues remain to be resolved, such as donor screening, manufacturing protocols, and unknown components in the fecal microbiota. In this review, we discuss the mechanisms, clinical indications, methods, and challenges of current FMT. We also discuss the development of alternative therapies to overcome the challenges of FMT.

Indexed as

Clostridioides difficileClostridium InfectionsFecal Microbiota TransplantationFecesGastrointestinal MicrobiomeAnimalsDysbiosisHumansClostridioides difficileFecal microbiota transplantationFecesGut microbiotaRecurrent C. difficile infection

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.