ArticleJournal of general internal medicine2025
Evaluation of a Tailored Patient Navigation Program for Improving Multitarget Stool DNA Test Adherence.
Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
backgroundMultitarget stool DNA (mt-sDNA) is an increasingly utilized noninvasive option for colorectal cancer screening; however, its impact is limited by imperfect test adherence. Tailored patient navigation (TPN) improves adherence for other cancer screening tests, but its role in mt-sDNA is not known.
aimDetermine whether TPN improves mt-sDNA completion and reduces sample could not be processed (SCNBP) result rates.
settingA large, urban, academic primary care clinic serving a medically vulnerable population.
participantsAll patients who received mt-sDNA order in 2022 and 2023. PROGRAM DESCRIPTION: A patient navigator outreached all patients ordered mt-sDNA to support test completion during the 12-month intervention period in 2023. PROGRAM EVALUATION: Rates of mt-sDNA completion within 90 days and SCNBP results were compared between the 12-month intervention and pre-intervention periods using generalized estimating equations. A total of 2694 patients received 3297 orders during the study. TPN was significantly associated with improved rates of 90-day mt-sDNA completion (51% vs. 39%, OR 1.67, p < .001) and SCNBP results (4% vs. 5%, OR 0.55, p < .001). DISCUSSION: Tailored patient navigation was associated with improved rates of mt-sDNA completion and SCNBP results despite built-in navigation services provided by the manufacturer. TPN for mt-sDNA is a promising strategy for enhancing colorectal cancer screening uptake.
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