ArticleAnnals of surgical oncology2025
Ultrasound Visualization of the Recurrent Laryngeal Nerve: A Prospective Clinical Validation Study.
Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Long-term outcomes and prognostic factors following microwave ablation vs surgical resection for primary hyperparathyroidism.European radiology · 2026Article
- A novel cartilage-based reference point for the recurrent laryngeal nerve: implication for preoperative risk stratification in posterior subcapsular thyroid tumors.World journal of surgical oncology · 2026Article
- A Comprehensive Exploration of Thyroid Nodules Diagnosis, Epidemiology and Pathophysiology with Emphasis on the Role of Traditional Chinese Medicine Treatment.International journal of general medicine · 2026Review
- The Sensory Gatekeeper of the Larynx: Anatomy and Clinical Importance of the Internal Branch of the Superior Laryngeal Nerve.Diagnostics (Basel, Switzerland) · 2025Review
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Authors and funding
10 authors.
Funding
Abstract
backgroundThis study aimed to optimize a lateral transthyroid approach by using high-resolution ultrasonography (HRUS) for recurrent laryngeal nerve (RLN) visualization. PATIENTS AND
methodsIn this prospective study of 85 patients undergoing thyroidectomy, the RLN was visualized preoperatively by using a lateral transthyroid approach via HRUS. The inferior thyroid artery, thyroid nodule, and cricoid cartilage were used as landmarks. RLN visibility was graded from poor to excellent. The accuracy of the preoperative localization of the RLN was determined by intraoperative HRUS, neuromonitoring, and surgical findings.
resultsRLN visualization and localization were verified intraoperatively by ultrasound-guided stimulation via a neuromonitoring probe in eight patients with extended incisions owing to the need for neck dissection. A total of 110 RLNs were present in 85 patients, and the locations of 103 RLNs detected by preoperative ultrasound were confirmed intraoperatively, with an accuracy rate of 93.6%. All detected RLNs were well visualized at the inferior thyroid artery and thyroid nodule levels. The RLN was visible in 83.5% of cases at the cricoid cartilage level. The maximum short-axis diameter and cross-sectional area of the RLN at all three levels were significantly larger in males than in females (p < 0.05). In total, ten RLNs were bifurcated and two showed tumor invasions. These findings were confirmed intraoperatively.
conclusionsEffective RLN visualization can be achieved using a lateral transthyroid approach via HRUS. The precise localization, prediction of anatomic variation, and invasion of RLN provide significant advantages in the individualized treatment, surgical planning, and nerve protection of patients with thyroid lesions.
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Registered trials
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