Evidence map›Paper›PMID 39557547›Full record

ArticleBMJ open2024

Behavioural economics to improve and motivate vaccination in primary care using nudges through the electronic health record: rationale and design of the BE IMMUNE randomised clinical trial.

Kimberly Waddell, Shivan J Mehta, Amol Navathe, Kristin Linn, Sae-Hwan Park, Andrew White, Jonathan Staloff, Corinne Rhodes, Chaylin Couzens, Keshav Goel and 4 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06057727 (BE IMMUNE), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06057727 nacompletednot on this map

BE IMMUNE: Behavioral Economics to IMprove and Motivate Vaccination Using Nudges Through the EHR

TypeinterventionalSponsorUniversity of PennsylvaniaRan2023 to 2024Enrolled80,039ConditionsBehavior, Health, Flu, Flu VaccinationArmsPre-visit patient text messaging, Default pended order, Monthly peer comparison feedback, High risk bidirectional pre-visit text messaging
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kimberly WaddellUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA kimberly.waddell@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0002-8137-2900
Shivan J MehtaUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Amol NavatheUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Kristin LinnUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Sae-Hwan ParkUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Andrew WhiteUniversity of Washington, Seattle, Washington, USA.
Jonathan StaloffUniversity of Washington, Seattle, Washington, USA.
Corinne RhodesUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Chaylin CouzensUniversity of Washington, Seattle, Washington, USA.
Keshav GoelUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Caitlin McDonaldUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Catherine ReitzUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Keyirah WilliamsUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Joshua M LiaoThe University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Funding

BE IMMUNE: Behavioral Economics to Improve and Motivate vaccination Using Nudges through the EHRR33AG068945 · NIA · UNIVERSITY OF PENNSYLVANIA · PI LIAO, JOSHUA M, MEHTA, SHIVAN JATIN · 2022 to 2024
$1.6M
NIA NIH HHS R33 AG068945
6 · The paper itself

Abstract

introductionAnnual influenza vaccination reduces disease burden but vaccination rates are suboptimal, with persistent disparities among subpopulations. The purpose of this trial is to evaluate multicomponent behavioural economic nudge interventions to clinicians and patients to increase influenza vaccination. This trial also includes an intensification nudge to reduce disparities in vaccination among older adult, primary care patients.

methodsThis is a two-part, multisite cluster randomised, pragmatic clinical trial. In the first part, a multicomponent nudge intervention will be tested over approximately 6 months (September 2023-February 2024). The second part consists of a replication trial conducted at an additional site during the following influenza season (September 2024-February 2025). Primary care clinics will be randomised to the nudge intervention or usual care. Eligible clinicians and patients at intervention clinics will receive the intervention, and patients deemed high risk for not receiving a vaccine will be further randomised to receive an intensification nudge. The primary outcome is vaccine completion during the eligible visit and the secondary outcome is vaccine completion within 3 months of the eligible visit. ANALYSIS: The effect of the clinic-level nudge intervention on the primary and secondary outcomes will be evaluated using generalised estimating equations (GEEs) with a clinic-level exchangeable working correlation to account for clustering of observations within the clinic. GEE models with an independent working correlation will be used to evaluate the impact of the additional intensification nudge on the primary and secondary outcomes. ETHICS AND DISSEMINATION: The University of Pennsylvania Institutional Review Board (IRB) approved this trial and serves as the single IRB of record (IRB #851838). Results will be disseminated via peer-reviewed publication and conference presentations. TRIAL REGISTRATION NUMBER: NCT06057727.

Indexed as

Economics, BehavioralElectronic Health RecordsInfluenza VaccinesMotivationPrimary Health CareVaccinationHumansInfluenza, HumanPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicInfluenza VaccinesBehaviorPREVENTIVE MEDICINEPrimary CareVaccination

Identifiers

PMID39557547
PMCPMC11574401

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.