Evidence map›Paper›PMID 39557333›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2025

Prognostic value of transient ischemic dilation on Rubidium-82 positron emission tomography myocardial perfusion imaging.

Krishna K Patel, Phillip Lim, Poghni A Peri-Okonny, Annapoorna Singh, A Iain McGhie, Basera Sabharwal, Vikram Agarwal, Leslee J Shaw, Timothy M Bateman

Abstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Transient ischemic dilation ratio by [The international journal of cardiovascular imaging · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Krishna K PatelDepartment of Medicine (Cardiology), Mount Sinai Fuster Hear Hospital, New York, NY, USA; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: Krishna.Patel5@mountsinai.org.
Phillip LimDepartment of Medicine (Cardiology), Mount Sinai Fuster Hear Hospital, New York, NY, USA.
Poghni A Peri-OkonnyDepartment of Medicine (Cardiology), Yale University School of Medicine, New Haven, CT, USA.
Annapoorna SinghSaint Luke's Mid America Heart Institute and University of Missouri-Kansas City, Kansas City, MO, USA.
A Iain McGhieSaint Luke's Mid America Heart Institute and University of Missouri-Kansas City, Kansas City, MO, USA.
Basera SabharwalDepartment of Medicine (Cardiology), Mount Sinai Fuster Hear Hospital, New York, NY, USA.
Vikram AgarwalDepartment of Medicine (Cardiology), Mount Sinai Fuster Hear Hospital, New York, NY, USA.
Leslee J ShawDepartment of Medicine (Cardiology), Mount Sinai Fuster Hear Hospital, New York, NY, USA.
Timothy M BatemanSaint Luke's Mid America Heart Institute and University of Missouri-Kansas City, Kansas City, MO, USA.

Funding

Residing in the Community with Dementia at the End of Life: Understanding Hospice Use and Residential SettingP30AG028741 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ORNA INTRATOR · 2010 to 2026
$21.9M
Re-thinking the Role of Stress Imaging for Symptomatic Older Adults with Stable Coronary Artery DiseaseR03AG082994 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PATEL, KRISHNA KAUSHIK · 2023 to 2024
$338k
NIA NIH HHS P30 AG028741NIA NIH HHS R03 AG082994
6 · The paper itself

Abstract

backgroundTransient ischemic dilation (TID) of the left ventricular (LV) cavity is considered a high-risk marker in patients with abnormal single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). Stress image acquisition with rubidium-82 (

methodsA total of 9878 consecutive patients with LVEF ≥40% undergoing rest/pharmacologic stress

resultsThe mean age of the cohort was 69.0 (11.7) years with 56.1% being female, 49.8% having known CAD, and 27.9% having abnormal perfusion (SSS>0). There were 451 cardiac deaths. Higher TID ratios were associated with higher risk of cardiac death, even after accounting for LVEF-R and MBFR (HR per .1 unit increase = 1.25 (1.11, 1.41), P < .001). This was seen in patients with both normal (HR for TID per .1 unit increase = 1.24 (95% CI: 1.01, 1.52), P = .04) and abnormal perfusion (HR for TID per .1 unit increase = 1.14 (95% CI: 1.02, 1.28), P = .03).

conclusionsTID on rest/stress

Indexed as

Myocardial IschemiaMyocardial Perfusion ImagingPositron-Emission TomographyRubidium RadioisotopesAgedCoronary Artery DiseaseFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesStroke VolumeRubidium-82Rubidium RadioisotopesMyocardial perfusion imagingPositron emission tomographyTransient ischemic dilation

Identifiers

PMID39557333
PMCPMC11830523

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.