Evidence map›Paper›PMID 39557293›Full record

ReviewThe journal of allergy and clinical immunology. In practice2025

Cough-Variant Asthma: A Review of Clinical Characteristics, Diagnosis, and Pathophysiology.

Joshua K Cox, Richard Lockey, Juan Carlos Cardet

Abstract readReview
In one paragraph

Review in The journal of allergy and clinical immunology. In practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Mechanisms and therapeutic strategies of asthma: from bench to bedside.Signal transduction and targeted therapy · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Effectiveness of the P2XJournal of asthma and allergy · 2026
    Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joshua K CoxDivision of Allergy and Immunology, University of South Florida, Tampa, Fla. Electronic address: jcox86@gmail.com.
Richard LockeyDivision of Allergy and Immunology, University of South Florida, Tampa, Fla.
Juan Carlos CardetDivision of Allergy and Immunology, University of South Florida, Tampa, Fla.

Funding

Social Determinants of Health, Asthma-Related Morbidity and Therapeutic Optimization for Black and Latinx Adults with AsthmaR21HL172124 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI CARDET, JUAN CARLOS · 2024 to 2025
$262k
NHLBI NIH HHS R21 HL172124
6 · The paper itself

Abstract

Chronic cough is among the most common symptoms prompting medical care. Cough-variant asthma (CVA) is an asthma subset where cough is the primary symptom, without wheezing, chest tightness, or dyspnea. It is an important cause of chronic cough, estimated to account for 25% to 42% of cases, but likely underdiagnosed due to delayed recognition and pitfalls of diagnostic testing. Early recognition and treatment can reduce morbidity and delay its progression to more typical asthma. This review details the clinical characteristics, diagnosis, pathophysiology, and treatment of CVA and contrasts it with classic asthma and other causes of chronic cough.

Indexed as

AsthmaCoughChronic DiseaseCough-Variant AsthmaDiagnosis, DifferentialHumansAirway remodelingAsthmaAsthma treatmentChronic coughCoughCough reflex sensitivityCough-variant asthmaEosinophilic airway inflammationNonasthmatic eosinophilic bronchitis

Identifiers

PMID39557293
PMCPMC12180285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.